{"id":"W1983774638","doi":"10.1039/c3cc46646a","title":"Selective trihydroxyazepane NagZ inhibitors increase sensitivity of Pseudomonas aeruginosa to β-lactams","year":2013,"lang":"en","type":"article","venue":"Chemical Communications","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Simon Fraser University","funders":"Canadian Institutes of Health Research","keywords":"Pseudomonas aeruginosa; Microbiology; Antibiotics; Bacteria; Lactam; Chemistry; Gram-negative bacteria; Biology; Stereochemistry; Escherichia coli; Biochemistry; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009227548,0.0002503046,0.0002410707,0.0002022997,0.0000839159,0.0002257906,0.0001497311,0.0001624809,0.001795212],"category_scores_gemma":[0.0001558508,0.0001106384,0.000135748,0.0001418297,0.0001403268,0.0001644807,0.0001668821,0.0004193776,0.0003221919],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002012327,"about_ca_system_score_gemma":0.0001595205,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005290043,"about_ca_topic_score_gemma":0.001051723,"domain_scores_codex":[0.9998515,0.00002144827,0.00001215296,0.00001644151,0.0000571314,0.00004134756],"domain_scores_gemma":[0.9998199,0.00003894685,0.00005292166,0.00001614515,0.00002861984,0.00004352595],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006856235,0.00002900976,0.00008654976,0.0000166106,0.000002843929,0.00001775379,0.000006836741,0.00003891357,0.998395,0.00001988775,0.0000248958,0.001293082],"study_design_scores_gemma":[0.000009257235,0.0004234649,0.001724465,0.00000252504,0.000006100643,0.00008798127,0.00001118987,0.0001809222,0.9964852,0.000007469427,0.001058356,0.000002955355],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993737,0.001891705,0.001669579,0.00008978709,0.00002207393,0.00004501356,0.0002021335,0.0001043033,0.002238447],"genre_scores_gemma":[0.9926088,0.001900817,0.001960085,0.00007871314,0.00001715361,0.00002853565,0.0003483678,0.00002419231,0.00303324],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001795212,"threshold_uncertainty_score":0.006005526,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0162806901006208,"score_gpt":0.2444274323493804,"score_spread":0.2281467422487596,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}