{"id":"W1983853688","doi":"10.1016/j.ejps.2005.08.007","title":"Drug permeability across a phospholipid vesicle based barrier: A novel approach for studying passive diffusion","year":2005,"lang":"en","type":"article","venue":"European Journal of Pharmaceutical Sciences","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":178,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal","funders":"Norges Forskningsråd; Knut och Alice Wallenbergs Stiftelse","keywords":"Phospholipid; Vesicle; Chemistry; Permeability (electromagnetism); Diffusion; Biophysics; Membrane; Biochemistry; Biology; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001885472,0.0001555263,0.0001761565,0.00002905846,0.0003382802,0.0000837067,0.000505059,0.00002694074,0.00003256004],"category_scores_gemma":[0.000174031,0.0001071159,0.0002024414,0.0001297167,0.000392788,0.00002298108,0.0001186924,0.000174934,0.000001767798],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002063991,"about_ca_system_score_gemma":0.0001043181,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":8.562855e-7,"about_ca_topic_score_gemma":9.211939e-7,"domain_scores_codex":[0.9984093,0.0001817085,0.0003864759,0.0003220635,0.0003302141,0.0003702388],"domain_scores_gemma":[0.9992161,0.00004138382,0.0001929436,0.0001357924,0.0001572998,0.000256465],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00020223,0.0002768225,0.001948058,0.00001773662,0.00001408591,0.000002665844,0.000252689,0.000494996,0.9644646,0.000006825097,0.0001676306,0.03215167],"study_design_scores_gemma":[0.002954642,0.0005577769,0.005373485,0.000017845,0.00006344388,0.00005883227,0.000545124,0.003003548,0.9288118,0.000001910038,0.05837967,0.0002318613],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9868442,0.0001635876,0.01155549,0.0004916671,0.0002633479,0.0002019088,0.00002627243,0.000006500594,0.0004470026],"genre_scores_gemma":[0.9858613,0.00001895326,0.01219383,0.0007616246,0.001070435,0.000003100261,0.000003733388,0.00001417389,0.00007286394],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05821203,"threshold_uncertainty_score":0.4368059,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04405056439264587,"score_gpt":0.3421935959520485,"score_spread":0.2981430315594026,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}