{"id":"W1983875761","doi":"10.1016/s1046-5928(02)00597-1","title":"Expression, purification, crystallization, and preliminary X-ray analysis of recombinant human saposin B","year":2002,"lang":"en","type":"article","venue":"Protein Expression and Purification","topic":"Enzyme Structure and Function","field":"Materials Science","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ontario Institute for Cancer Research; University of Toronto","funders":"National Center for Research Resources; National Institute of Neurological Disorders and Stroke; Canadian Institutes of Health Research","keywords":"Chemistry; Crystallization; Biochemistry; Dimer; Maltose-binding protein; Escherichia coli; Recombinant DNA; Fusion protein; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003700053,0.0001746613,0.0002701996,0.0003026241,0.0003677374,0.00008009958,0.0001457745,0.0001514926,0.0008376355],"category_scores_gemma":[0.00009443005,0.0001435123,0.00004829104,0.0004741878,0.0001315483,0.0003702,0.00005053284,0.00008980931,0.000007336647],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001626687,"about_ca_system_score_gemma":0.000007611424,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002280473,"about_ca_topic_score_gemma":0.000002909496,"domain_scores_codex":[0.9983348,0.0001964171,0.0005248754,0.0004972911,0.0002794118,0.0001671688],"domain_scores_gemma":[0.9987771,0.00004283657,0.0004236522,0.0004544759,0.0001981953,0.0001037762],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003822903,0.0000993079,0.0008250307,0.00006852591,0.00001430656,2.884297e-7,0.0009848031,0.00005557207,0.9940822,0.001158523,0.001007367,0.001665865],"study_design_scores_gemma":[0.0004253784,0.0001529334,0.02993847,0.0001441917,0.00016665,0.000002230707,0.0001788335,0.00166026,0.9626059,0.001189262,0.003298092,0.0002378094],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9784141,0.00187699,0.01774026,0.0003448918,0.0001395046,0.0007532151,0.00001744073,0.0001016374,0.0006119389],"genre_scores_gemma":[0.9931422,0.0001857888,0.005250446,0.00002775882,0.00004217844,0.0001486172,0.00009176883,0.0000156534,0.001095525],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03147629,"threshold_uncertainty_score":0.9171521,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01800602337599018,"score_gpt":0.2394408193364501,"score_spread":0.2214347959604599,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}