{"id":"W1983895021","doi":"10.1359/jbmr.2002.17.4.639","title":"Proteolysis Involving Matrix Metalloproteinase 13 (Collagenase-3) Is Required for Chondrocyte Differentiation That Is Associated with Matrix Mineralization","year":2002,"lang":"en","type":"article","venue":"Journal of Bone and Mineral Research","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":122,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Shriners Hospitals for Children - Canada","funders":"Canadian Institutes of Health Research; Health Canada; National Institutes of Health; Shriners Hospitals for Children; McGill University","keywords":"Chondrocyte; Extracellular matrix; Collagenase; Cell biology; Matrix metalloproteinase; Type II collagen; Chemistry; Cartilage; Interstitial collagenase; Calcification; Proteolysis; Matrix (chemical analysis); Endochondral ossification; Type I collagen; Biology; Biochemistry; Endocrinology; Internal medicine; Anatomy; Enzyme; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008147671,0.0001884838,0.0005550341,0.000597154,0.0002275625,0.0001196649,0.00005764865,0.0001434689,0.0002317563],"category_scores_gemma":[0.0003481607,0.0001332741,0.0001868737,0.0004702735,0.00005801685,0.0003824821,0.00003301465,0.0002357551,0.000005147507],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000151117,"about_ca_system_score_gemma":0.0000784099,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005413522,"about_ca_topic_score_gemma":0.0001201078,"domain_scores_codex":[0.9978102,0.0001201948,0.0004740269,0.0002363208,0.0009480235,0.0004112077],"domain_scores_gemma":[0.9981912,0.0001040713,0.000346365,0.0001660158,0.0009422583,0.000250066],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002173052,0.0008108388,0.002395777,0.0003446493,0.0007163656,0.0006384494,0.001912753,0.000003547205,0.9713032,0.0001666622,0.01237539,0.007159282],"study_design_scores_gemma":[0.09096178,0.05269956,0.007066926,0.006085441,0.004560181,0.002355272,0.002748212,0.01753761,0.8015739,0.002154942,0.0107704,0.001485739],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905989,0.005234053,0.0002471503,0.002423914,0.00005045588,0.001305179,0.0000258785,0.00001425239,0.0001001774],"genre_scores_gemma":[0.9600506,0.0009736213,0.002215646,0.000107521,0.0001982858,0.00008825284,0.00004415194,0.00003942207,0.03628247],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1697293,"threshold_uncertainty_score":0.5434758,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08015490832948562,"score_gpt":0.3385609828527374,"score_spread":0.2584060745232518,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}