{"id":"W1983939667","doi":"10.1021/pr050215d","title":"Differential Dimethyl Labeling of N-Termini of Peptides after Guanidination for Proteome Analysis","year":2005,"lang":"en","type":"article","venue":"Journal of Proteome Research","topic":"Advanced Proteomics Techniques and Applications","field":"Chemistry","cited_by":107,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Chemistry; Peptide; Chromatography; Proteome; Mass spectrometry; Reductive amination; Matrix-assisted laser desorption/ionization; Isobaric labeling; Lysine; Tandem mass spectrometry; Amino acid; Protein mass spectrometry; Desorption; Biochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001243333,0.0001284762,0.0004681094,0.0006571492,0.00008750111,0.00002771384,0.0004308769,0.000140151,0.0003599783],"category_scores_gemma":[0.0003762203,0.0001088182,0.0003686143,0.0006722905,0.0001412478,0.0002114951,0.0001111741,0.0004746435,0.000001262905],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001309809,"about_ca_system_score_gemma":0.0001240289,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001133745,"about_ca_topic_score_gemma":0.000004640114,"domain_scores_codex":[0.997791,0.00005549582,0.0009356408,0.0001920484,0.0007259571,0.0002998747],"domain_scores_gemma":[0.9969802,0.0002163749,0.0007589743,0.0003341064,0.001613732,0.00009656571],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003774489,0.0002528051,0.001005133,0.0003865389,0.0002379589,0.000001537233,0.0001559966,0.0001163847,0.9922808,0.000234283,0.00002907226,0.004922],"study_design_scores_gemma":[0.0005272567,0.0002139931,0.0003053072,0.0001676084,0.0001333723,0.00000580455,0.00007290805,0.001219106,0.9926633,0.003996055,0.00059324,0.0001020015],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9057724,0.0001733904,0.09274086,0.0003773023,0.000007603076,0.0006978796,0.0000511818,0.00001045875,0.0001689528],"genre_scores_gemma":[0.8052641,0.00008533726,0.1936295,0.000001971977,0.0002105098,0.0003646192,0.000005102138,0.00002023123,0.0004186534],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1008887,"threshold_uncertainty_score":0.4437478,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0523720855928441,"score_gpt":0.4135445281505572,"score_spread":0.3611724425577131,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}