{"id":"W1984029360","doi":"10.1074/jbc.m113.479550","title":"DEAF1 Is a Pellino1-interacting Protein Required for Interferon Production by Sendai Virus and Double-stranded RNA*","year":2013,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital","funders":"Medical Research Council; Canadian Institutes of Health Research; Wellcome Trust","keywords":"IRF3; Sendai virus; MDA5; IRF7; Ubiquitin ligase; Interferon regulatory factors; Biology; Molecular biology; Interferon; TLR3; Transcription factor; Transcription (linguistics); RNA silencing; TANK-binding kinase 1; Cell biology; Phosphorylation; RNA; Virology; Gene; RNA interference; Virus; Ubiquitin; Protein kinase A; Receptor; Toll-like receptor; Biochemistry; Cyclin-dependent kinase 2; Innate immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003276651,0.0001954709,0.0003745753,0.00003238015,0.0001079796,0.00004214516,0.0001816152,0.0003443456,0.0009014557],"category_scores_gemma":[0.0002543049,0.0001308378,0.0001654437,0.00003489774,0.0001811497,0.0001625369,0.00005186662,0.0004656344,0.0000331872],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004717216,"about_ca_system_score_gemma":0.00003063158,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001412167,"about_ca_topic_score_gemma":3.065261e-7,"domain_scores_codex":[0.9987818,0.00008225427,0.0005824717,0.0002349368,0.00003392992,0.0002845796],"domain_scores_gemma":[0.9990649,0.000128022,0.0004438906,0.000124553,0.0001963468,0.00004234011],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00442822,0.0001325698,0.00004053853,0.00004994223,0.0001333555,0.000001657393,0.0001203573,1.833568e-7,0.9835169,0.000002266651,0.007932884,0.003641106],"study_design_scores_gemma":[0.001756699,0.0008215448,0.00004675203,0.0001425199,0.00002306455,0.0004659723,0.000408398,0.000002909111,0.9790499,0.00009341718,0.01703495,0.0001539178],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957514,0.001899892,0.000253629,0.00120773,0.0002944474,0.0003199992,0.00001698355,0.00001972205,0.0002361903],"genre_scores_gemma":[0.9947492,0.0001579635,0.0001656677,0.0000936024,0.0001174214,0.00002666376,0.00002061106,0.00001059014,0.004658258],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009102066,"threshold_uncertainty_score":0.9870307,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02992348572770441,"score_gpt":0.2704549694163267,"score_spread":0.2405314836886223,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}