{"id":"W1984037038","doi":"10.1038/nchembio.1414","title":"Seeing is believing","year":2013,"lang":"en","type":"letter","venue":"Nature Chemical Biology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":380,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Palmitoylation; Bioorthogonal chemistry; Acyltransferase; Chemistry; Biochemistry; Computational biology; Click chemistry; Biology; Combinatorial chemistry; Cysteine; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0001071629,0.0003887844,0.0003607643,0.00006624448,0.00005221602,0.00002975219,0.000459299,0.007415826,0.0001915779],"category_scores_gemma":[0.0002350888,0.0003444469,0.0002278737,0.00008252379,0.0001310446,0.000001727746,0.0002712661,0.002581303,0.00009645352],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002845814,"about_ca_system_score_gemma":0.00006040572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009617491,"about_ca_topic_score_gemma":5.909164e-7,"domain_scores_codex":[0.9981268,0.00007749655,0.0003157397,0.0008393103,0.000133909,0.0005067539],"domain_scores_gemma":[0.9989383,0.00005587135,0.0001811284,0.0005851542,0.0001687717,0.00007077176],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000003567745,0.000005379942,0.0002305722,0.00002631574,0.00004678983,0.000003324199,0.000003955477,9.227796e-8,0.5306611,0.000008008302,0.4670067,0.002004151],"study_design_scores_gemma":[0.0001007115,0.00004203905,0.00001431695,0.00001236095,0.00001804904,0.000003627,7.262142e-7,0.000003047545,0.4049081,0.0004860973,0.5941606,0.0002503827],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.2474854,0.09914297,0.0007316548,0.6305293,0.003480863,0.001083152,0.0004286061,0.0001338778,0.01698412],"genre_scores_gemma":[0.1190924,0.001536649,0.002053614,0.849632,0.01553813,0.00006680645,0.008584065,0.0001344475,0.003361908],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.2191026,"threshold_uncertainty_score":0.9999008,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006876849687388098,"score_gpt":0.262543681180788,"score_spread":0.2556668314933999,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}