{"id":"W1984051873","doi":"10.1002/1521-4141(200012)30:12<3723::aid-immu3723>3.0.co;2-9","title":"Adhesion mediated by LFA-1 is required for efficient IL-12-induced NK and NKT cell cytotoxicity","year":2000,"lang":"en","type":"article","venue":"European Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"Amgen (Canada); University of Toronto; Ontario Institute for Cancer Research","funders":"","keywords":"Biology; Cytotoxic T cell; Natural killer T cell; Cell biology; Interleukin 12; Lymphocyte function-associated antigen 1; Perforin; Lymphokine-activated killer cell; Interleukin 21; Cell adhesion molecule; Cancer research; In vitro; Intercellular Adhesion Molecule-1; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0007905429,0.0002307097,0.0003939569,0.0001814161,0.0002515137,0.00002374971,0.0002633225,0.0001639868,0.002497614],"category_scores_gemma":[0.000136989,0.0001956823,0.0001775362,0.00008904025,0.0001615297,0.0001236281,0.00005000817,0.0005483426,0.000854128],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000572011,"about_ca_system_score_gemma":0.00003976656,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007280365,"about_ca_topic_score_gemma":3.042334e-7,"domain_scores_codex":[0.9977168,0.0008414526,0.0007758441,0.0002537039,0.00004938069,0.0003628225],"domain_scores_gemma":[0.9988494,0.0001948722,0.0005047061,0.0002360238,0.0001767031,0.00003833002],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001944853,0.0002015659,0.00003823715,0.00001018392,0.0001661032,0.00001254141,0.0006149374,0.000003353181,0.9548156,0.000005358496,0.03664823,0.005538999],"study_design_scores_gemma":[0.00536405,0.003156341,0.002302978,0.00005874545,0.00007198603,0.0005858943,0.0003173662,0.00002052302,0.7230138,0.000003780606,0.2648703,0.0002341881],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9894219,0.003691083,0.000346156,0.0005542443,0.001925166,0.0002027723,0.00001887663,0.00003710997,0.003802717],"genre_scores_gemma":[0.9883126,0.0008907827,0.00006685628,0.0006504073,0.00006405739,0.000002464326,0.00004866176,0.00003928819,0.009924865],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2318018,"threshold_uncertainty_score":0.9999238,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0139535612913096,"score_gpt":0.2179681872342026,"score_spread":0.204014625942893,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}