{"id":"W1984051873","doi":"10.1002/1521-4141(200012)30:12<3723::aid-immu3723>3.0.co;2-9","title":"Adhesion mediated by LFA-1 is required for efficient IL-12-induced NK and NKT cell cytotoxicity","year":2000,"lang":"en","type":"article","venue":"European Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"Amgen (Canada); University of Toronto; Ontario Institute for Cancer Research","funders":"","keywords":"Biology; Cytotoxic T cell; Natural killer T cell; Cell biology; Interleukin 12; Lymphocyte function-associated antigen 1; Perforin; Lymphokine-activated killer cell; Interleukin 21; Cell adhesion molecule; Cancer research; In vitro; Intercellular Adhesion Molecule-1; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001332587,0.0003336189,0.000315341,0.0001987151,0.0002257217,0.0007175847,0.0001744871,0.0003590652,0.002483772],"category_scores_gemma":[0.000360858,0.0002021614,0.0002004981,0.0001296201,0.0002148748,0.0002728199,0.0003384466,0.0006344577,0.001420356],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004300874,"about_ca_system_score_gemma":0.0002540709,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005794786,"about_ca_topic_score_gemma":0.0006088461,"domain_scores_codex":[0.9996717,0.00006691479,0.00002986721,0.00003709746,0.00007120903,0.0001230999],"domain_scores_gemma":[0.9997267,0.0000400183,0.00009690245,0.00003593092,0.00002974974,0.00007062058],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008253298,0.00002510521,0.0003511618,0.00002185068,0.000002941599,0.000110256,0.000009906231,0.00006350132,0.9982486,0.00007612248,0.00003923524,0.0009687843],"study_design_scores_gemma":[0.00004557503,0.0002174023,0.01894399,0.00001575345,0.00002091502,0.001211431,0.00005855272,0.001697354,0.9747166,0.000125346,0.002939547,0.000007526492],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960003,0.0009992264,0.001706244,0.00008511039,0.00001808724,0.00001451395,0.0001509531,0.00007501044,0.0009504253],"genre_scores_gemma":[0.997411,0.0002869374,0.0007125547,0.00002818673,0.000005300309,0.00002234495,0.0003648273,0.00001670373,0.001152176],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002483772,"threshold_uncertainty_score":0.008309066,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0139535612913096,"score_gpt":0.2179681872342026,"score_spread":0.204014625942893,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}