{"id":"W1984060790","doi":"10.4161/auto.5432","title":"Is mitochondrial generation of reactive oxygen species a trigger for autophagy?","year":2008,"lang":"en","type":"review","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":234,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Autophagy; Reactive oxygen species; Superoxide; Cell biology; Peroxynitrite; Programmed cell death; Mitochondrial ROS; Mitochondrion; Biology; Apoptosis; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004195461,0.0007183104,0.002131765,0.001177338,0.000267095,0.0009299265,0.0008176235,0.001756802,0.001869923],"category_scores_gemma":[0.000574469,0.0001914076,0.0004107254,0.001092551,0.0007246741,0.001666758,0.0003810474,0.001182538,0.002137388],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007144313,"about_ca_system_score_gemma":0.0006096329,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000315097,"about_ca_topic_score_gemma":0.000466952,"domain_scores_codex":[0.9998161,0.00003658177,0.00002821439,0.00003864741,0.00006179627,0.00001865332],"domain_scores_gemma":[0.9997132,0.0001236854,0.00004879387,0.00001233586,0.00007067817,0.00003125313],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001707816,0.00009464453,0.0007649946,0.01519871,0.0001585726,0.002562518,0.0001227199,0.0002156343,0.009084948,0.00748797,0.04200725,0.9221313],"study_design_scores_gemma":[0.00006235248,0.0002908884,0.003631328,0.004869334,0.0002246466,0.02053002,0.0003624128,0.0002028855,0.006250815,0.01284385,0.9506749,0.00005653948],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003079837,0.9969918,0.000232723,0.0009334646,0.0005074781,0.000004048728,0.00001063271,0.00001161654,0.001000216],"genre_scores_gemma":[0.002302853,0.9957001,0.0001771401,0.0005239387,0.0006611411,0.000007388902,0.00001492669,0.000001502017,0.0006110504],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002131765,"threshold_uncertainty_score":0.006255507,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1477848975089179,"score_gpt":0.3826120320466178,"score_spread":0.2348271345376999,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}