{"id":"W1984095180","doi":"10.1016/j.virol.2005.10.044","title":"Lentivirus envelope protein exerts differential neuropathogenic effects depending on the site of expression and target cell","year":2006,"lang":"en","type":"article","venue":"Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta; University of Calgary","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Biology; Lentivirus; Extracellular; Endoplasmic reticulum; Infectivity; Microglia; Intracellular; Downregulation and upregulation; Neuroinflammation; Feline immunodeficiency virus; Virology; Cell biology; Immunology; Virus; Inflammation; Gene; Biochemistry; Viral disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001087645,0.0001479408,0.000217084,0.00008391981,0.000170849,0.000006842087,0.00009591452,0.0001417978,0.0003016273],"category_scores_gemma":[0.0000322996,0.00009021384,0.0000542345,0.00004789692,0.0001912168,0.00002459794,0.0001228304,0.0002156536,0.0003721066],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009813364,"about_ca_system_score_gemma":0.00001491091,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005175923,"about_ca_topic_score_gemma":0.00001155132,"domain_scores_codex":[0.9985993,0.0006051107,0.0001559915,0.0002648879,0.00003918775,0.0003355573],"domain_scores_gemma":[0.9994009,0.00028063,0.00007844853,0.000209662,0.00001258498,0.00001776455],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003166037,0.0002394139,0.004240848,0.00002275094,0.00002204975,0.000052322,0.00004908868,0.000001495701,0.9936926,0.0002083765,0.000492177,0.0006622543],"study_design_scores_gemma":[0.001287818,0.0005984267,0.08169457,0.00001642409,0.00001622484,0.00001930478,0.000003940632,0.000002321704,0.9141118,0.0001629579,0.002012091,0.00007415094],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971488,0.001170633,0.0001420051,0.0001026905,0.0001276242,0.0004961842,0.00004016726,0.00002050467,0.0007514497],"genre_scores_gemma":[0.9987407,0.00002800549,0.00003324934,0.00003213879,0.0000207699,0.00008190674,0.00007412672,0.00001287519,0.0009762351],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07958085,"threshold_uncertainty_score":0.4782801,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005644377298684879,"score_gpt":0.1970631629208328,"score_spread":0.1914187856221479,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}