{"id":"W1984124391","doi":"10.1016/j.taap.2007.08.013","title":"DNA methylation analysis using CpG microarrays is impaired in benzopyrene exposed cells","year":2007,"lang":"en","type":"article","venue":"Toxicology and Applied Pharmacology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University; Children’s Health Research Institute; London Health Sciences Centre","funders":"Canadian Institutes of Health Research; Lawson Health Research Institute","keywords":"DNA methylation; Epigenetics; Methylated DNA immunoprecipitation; Biology; DNA microarray; Epigenetics of physical exercise; CpG site; Illumina Methylation Assay; Epigenomics; Microarray; Genetics; Molecular biology; Carcinogenesis; DNA; Methylation; Bisulfite sequencing; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007561775,0.0002104256,0.0003325029,0.000336877,0.0001085638,0.00001032657,0.0001215727,0.0004575236,0.0001939334],"category_scores_gemma":[0.000007595032,0.0002291735,0.0000878924,0.0004352797,0.0001433484,0.000004227312,0.00009344143,0.0001629819,0.000004539828],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003568974,"about_ca_system_score_gemma":0.00005216362,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001655945,"about_ca_topic_score_gemma":0.0001209646,"domain_scores_codex":[0.9984435,0.0001106566,0.0004182573,0.0005184643,0.00007476747,0.0004343468],"domain_scores_gemma":[0.9994389,0.00006953897,0.0001645039,0.0001662165,0.00004203803,0.0001188019],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003160497,0.0001193693,0.002804597,0.000007941875,0.0002492201,0.000004870968,0.0001870794,0.001587179,0.9919785,0.00006431335,0.00008779213,0.002593106],"study_design_scores_gemma":[0.001377892,0.0001500446,0.01050895,9.320468e-7,0.0002942877,0.000001873462,0.00007982209,0.0009653743,0.984844,0.0003280236,0.00121751,0.0002312897],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9837558,0.0008473208,0.01420914,0.00009228436,0.0001949297,0.000307292,0.00001409855,0.00001248676,0.0005666898],"genre_scores_gemma":[0.9967675,0.0001984994,0.002000768,0.0006714925,0.0001881408,0.00002579778,0.00006916851,0.00001926148,0.00005941619],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0130117,"threshold_uncertainty_score":0.9345425,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02015782646544918,"score_gpt":0.3059168890069728,"score_spread":0.2857590625415237,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}