{"id":"W1984147340","doi":"10.1007/s00109-011-0788-5","title":"From oncoproteins/tumor suppressors to microRNAs, the newest therapeutic targets for pulmonary arterial hypertension","year":2011,"lang":"en","type":"review","venue":"Journal of Molecular Medicine","topic":"Pulmonary Hypertension Research and Treatments","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval; Hôtel-Dieu de Québec","funders":"Canadian Institutes of Health Research; World Health Organization","keywords":"Cancer research; microRNA; Pulmonary hypertension; Cancer; Pulmonary artery; BMPR2; Medicine; Molecular medicine; Suppressor; Pathogenesis; Phenotype; Biology; Bioinformatics; Immunology; Internal medicine; Cell cycle; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007254491,0.0006765002,0.003222894,0.0004944802,0.0001384141,0.00002138436,0.0006447427,0.000285063,0.0003434244],"category_scores_gemma":[0.0006543325,0.000320648,0.00107826,0.0003353059,0.0002093312,0.00006842405,0.0001235129,0.0008812078,0.00006047659],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001705348,"about_ca_system_score_gemma":0.000740809,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001380004,"about_ca_topic_score_gemma":0.00000220301,"domain_scores_codex":[0.9961732,0.0003651752,0.001417492,0.0004929645,0.0009542877,0.0005968575],"domain_scores_gemma":[0.9963086,0.0004095518,0.0009234045,0.0008430304,0.0006911494,0.0008242573],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002949742,0.001255933,0.000004812045,0.002690097,0.003527695,0.03934224,0.0001368068,2.958172e-7,0.02670338,0.00001316217,0.01863279,0.9047431],"study_design_scores_gemma":[0.00284661,0.003146738,0.0000797527,0.01670721,0.005559235,0.01092226,0.00008173626,0.000005033678,0.0003874325,0.0002433992,0.9597531,0.0002674697],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0008656542,0.9911497,0.0003101958,0.003294721,0.001264278,0.002877671,0.0000925613,0.00001591724,0.0001292527],"genre_scores_gemma":[0.001109797,0.9902707,0.001408309,0.003321104,0.003004254,0.0001442079,0.0002566307,0.000171185,0.0003138242],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9411203,"threshold_uncertainty_score":0.9999245,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07299394228366979,"score_gpt":0.3470188786414825,"score_spread":0.2740249363578127,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}