{"id":"W1984188458","doi":"10.1021/jo0160930","title":"Synthesis and Membrane Activity of a Bis(metacyclophane)bolaamphiphile","year":2002,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Membrane; Dimer; Bilayer; Derivative (finance); Stereochemistry; Conductance; Axial symmetry; Octane; Organic chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002865464,0.0001462773,0.0002440202,0.00001206404,0.00005252655,0.000009285062,0.0003374614,0.000137879,0.0006720814],"category_scores_gemma":[0.0002851578,0.0001057765,0.0001029895,0.00008755369,0.0001685238,0.000006494457,0.0001108801,0.0001786232,0.000001549756],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001210309,"about_ca_system_score_gemma":0.00004100102,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001456458,"about_ca_topic_score_gemma":4.570199e-7,"domain_scores_codex":[0.9992351,0.0000345229,0.0002741885,0.0001191852,0.0001854585,0.000151553],"domain_scores_gemma":[0.999053,0.00006568585,0.0003623837,0.0003321267,0.00009290794,0.00009386534],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000092248,0.00008720547,0.0001480808,0.00008498505,0.0001207891,0.00000469304,0.00005121484,0.000001497747,0.9972879,2.248305e-7,0.0007873908,0.001333741],"study_design_scores_gemma":[0.0003617206,0.00004774273,0.0001487113,0.00003266853,0.0001246016,0.0006908956,0.00009126455,0.00001102703,0.9959188,0.000007914379,0.002454039,0.0001106358],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954391,0.002214658,0.00005553408,0.0003301862,0.00003654335,0.00002834395,0.000007855179,0.000003551527,0.001884227],"genre_scores_gemma":[0.9968882,0.002063583,0.0000999624,0.00003571272,0.0002403512,6.474229e-7,8.63932e-7,0.00002061043,0.0006500485],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001666648,"threshold_uncertainty_score":0.735882,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007870445133407953,"score_gpt":0.198187251208504,"score_spread":0.190316806075096,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}