{"id":"W1984188550","doi":"10.1210/endo.143.4.8753","title":"Increased Islet Cell Proliferation, Decreased Apoptosis, and Greater Vascularization Leading to β-Cell Hyperplasia in Mutant Mice Lacking Insulin","year":2002,"lang":"en","type":"article","venue":"Endocrinology","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":83,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; Lawson Health Research Institute","funders":"Canadian Institutes of Health Research; Juvenile Diabetes Research Foundation Canada; Lawson Health Research Institute; Juvenile Diabetes Research Foundation International","keywords":"Internal medicine; Endocrinology; Islet; Insulin; Biology; Neogenesis; Pancreas; Beta cell; Enteroendocrine cell; Endocrine system; Hormone; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009044788,0.0001832777,0.0003540632,0.0003727805,0.00007274484,0.00002509688,0.00005269742,0.0000990177,0.0003590721],"category_scores_gemma":[0.000278559,0.0001727781,0.00004030931,0.0002976149,0.00004196611,0.00008083604,0.00003617797,0.0001716438,0.0002150134],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007331338,"about_ca_system_score_gemma":0.00002889202,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001332275,"about_ca_topic_score_gemma":0.00001213531,"domain_scores_codex":[0.9986742,0.0001171241,0.0003107803,0.0003752082,0.0001346466,0.0003880832],"domain_scores_gemma":[0.9993933,0.0001013841,0.00005792174,0.000206288,0.00006681919,0.0001742425],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002049555,0.0003898485,0.4867565,0.0001475701,0.00003911776,0.0000748754,0.001169604,0.00004958241,0.5084739,0.000158164,0.0008871128,0.001648789],"study_design_scores_gemma":[0.009910501,0.0005687634,0.03545817,0.0001104672,0.0001614977,0.0002312608,0.0003310111,0.00456441,0.9428685,0.00004797135,0.005341182,0.000406216],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927815,0.0004078682,0.0003604798,0.0008719647,0.0001030416,0.0004873841,0.000004102881,0.00008168901,0.004902017],"genre_scores_gemma":[0.9958006,0.0001090581,0.001116038,0.002159938,0.00009602659,0.00007009655,0.00003820233,0.00002447946,0.0005855248],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4512984,"threshold_uncertainty_score":0.7045686,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01607871315084856,"score_gpt":0.2303159175209571,"score_spread":0.2142372043701086,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}