{"id":"W1984214335","doi":"10.1515/bc.2003.157","title":"Transcription of Cathepsin B in Glioma Cells: Regulation by an E-Box Adjacent to the Transcription Initiation Site","year":2003,"lang":"en","type":"article","venue":"Biological Chemistry","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Windsor","funders":"National Cancer Institute; U.S. Forest Service; National Institutes of Health","keywords":"Molecular biology; Chromatin immunoprecipitation; Transcription factor; Promoter; Transcription (linguistics); Enhancer; Transactivation; E-box; Transfection; Biology; Chemistry; Gene expression; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001471826,0.0004560026,0.0003217815,0.0003779304,0.0002128108,0.0003744326,0.000154008,0.0002187279,0.0007505858],"category_scores_gemma":[0.0001626095,0.0002173707,0.0003461853,0.0002406617,0.000298878,0.0001430522,0.0002702451,0.0004618605,0.0006242052],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004835814,"about_ca_system_score_gemma":0.0003956244,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003409966,"about_ca_topic_score_gemma":0.003576468,"domain_scores_codex":[0.9998247,0.00002870742,0.00001459571,0.00004467809,0.00004752317,0.00003980499],"domain_scores_gemma":[0.9998714,0.00002394483,0.00002530678,0.00001490106,0.00002196516,0.00004256603],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009003421,0.00001692991,0.0002648853,0.00002109582,0.000002137398,0.0000268072,0.00001846155,0.00002185442,0.9987155,0.00004306873,0.00003042315,0.0007488997],"study_design_scores_gemma":[0.00003060058,0.000134027,0.009958269,0.00001083664,0.0000111415,0.0002671158,0.00005500263,0.001167178,0.9858952,0.0000532906,0.002409919,0.000007382847],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9893795,0.002672489,0.005945888,0.000120717,0.00003144395,0.00002844028,0.0006238277,0.0001602324,0.001037584],"genre_scores_gemma":[0.9846644,0.001328865,0.008954545,0.00006887595,0.00001707572,0.00005724924,0.002287084,0.00005139135,0.002570683],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003409966,"threshold_uncertainty_score":0.006780207,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01389901449961953,"score_gpt":0.221988286156501,"score_spread":0.2080892716568815,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}