{"id":"W1984230040","doi":"10.1016/j.ab.2009.10.047","title":"Enrichment of serum low-molecular-weight proteins using C18 absorbent under urea/dithiothreitol denatured environment","year":2009,"lang":"en","type":"article","venue":"Analytical Biochemistry","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Key Research and Development Program of China; National Natural Science Foundation of China; Canadian Institute for Theoretical Astrophysics","keywords":"Dithiothreitol; Urea; Chemistry; Chromatography; Biochemistry; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006807023,0.0007298055,0.000615322,0.0005053701,0.0004597045,0.0004494354,0.0004854394,0.0003293539,0.00133586],"category_scores_gemma":[0.0005668795,0.0002483032,0.0003835564,0.0005225266,0.0002723711,0.0002637169,0.0003594213,0.0006827849,0.001542873],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004234157,"about_ca_system_score_gemma":0.0006575193,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002075557,"about_ca_topic_score_gemma":0.002577325,"domain_scores_codex":[0.9995678,0.00007150622,0.00006084509,0.0000780102,0.0001049116,0.0001169437],"domain_scores_gemma":[0.9996032,0.00006661281,0.00003556212,0.00006579381,0.000169614,0.00005930409],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001161914,0.00002604175,0.0002234913,0.00003730725,0.000005590916,0.00004407563,0.00002704102,0.00001928065,0.9976963,0.00006035253,0.0001152834,0.001628989],"study_design_scores_gemma":[0.000007899867,0.00007607527,0.001420071,0.000005564116,0.00001239735,0.0001604375,0.00001069808,0.0004920145,0.9947308,0.00004911085,0.003030588,0.000004149754],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8930318,0.004191751,0.09502289,0.0008995535,0.0002610838,0.0003757746,0.00143849,0.001771607,0.003007004],"genre_scores_gemma":[0.7988395,0.004525791,0.1683585,0.0006511384,0.0001828492,0.0004343705,0.009298036,0.0006638207,0.01704598],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002075557,"threshold_uncertainty_score":0.004468918,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007703113656184893,"score_gpt":0.2542636534913867,"score_spread":0.2465605398352018,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}