{"id":"W198435100","doi":"10.1016/s0301-472x(02)00815-9","title":"Clonal evolution in marrows of patients with Shwachman-Diamond syndrome","year":2002,"lang":"en","type":"article","venue":"Experimental Hematology","topic":"Blood disorders and treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":83,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Cytopenia; Medicine; Myelodysplastic syndromes; Myeloid leukemia; Bone marrow; CD34; Bone marrow failure; Myeloid; Internal medicine; Pancytopenia; Trisomy 8; Stem cell; Immunology; Gastroenterology; Haematopoiesis; Cytogenetics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002030843,0.0002497454,0.0002556591,0.001037601,0.000392854,0.00032918,0.0002553422,0.0004091466,0.001713351],"category_scores_gemma":[0.001332297,0.0001739514,0.000103335,0.0003772238,0.0002480638,0.000202427,0.0002815454,0.0001963507,0.0002411024],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001849889,"about_ca_system_score_gemma":0.0001288264,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001218252,"about_ca_topic_score_gemma":0.0007406577,"domain_scores_codex":[0.9998676,0.00002924826,0.0000172893,0.00002440276,0.00003273938,0.00002875096],"domain_scores_gemma":[0.9996477,0.0001425446,0.00005855835,0.00002434564,0.00005890911,0.00006798183],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00415949,0.0002924184,0.6414644,0.0001483307,0.0001033402,0.06001839,0.002528848,0.0005889717,0.2623559,0.0009610138,0.0005315745,0.02684741],"study_design_scores_gemma":[0.0002132142,0.001290843,0.8693551,0.0000313276,0.0001686847,0.1002182,0.001665647,0.0009169919,0.02320294,0.0006273689,0.002283901,0.00002569828],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988967,0.0003261348,0.00009978464,0.00002209715,0.00000350211,0.000008844395,0.00007993863,0.000005945496,0.0005570271],"genre_scores_gemma":[0.9994897,0.0001236275,0.0001014883,0.00002562614,0.000006351121,0.000006101264,0.00008339412,0.000003216054,0.0001605245],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001713351,"threshold_uncertainty_score":0.005731761,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004825339906228326,"score_gpt":0.2113915852877866,"score_spread":0.2065662453815582,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}