{"id":"W1984395407","doi":"10.1023/b:drug.0000006171.54078.3d","title":"The Antiangiogenic Agent Neovastat (Æ-941) Stimulates Tissue Plasminogen Activator Activity","year":2003,"lang":"en","type":"article","venue":"Investigational New Drugs","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université du Québec à Montréal","funders":"","keywords":"Plasmin; Plasminogen activator; Urokinase; Angiogenesis; Tissue plasminogen activator; Chemistry; In vitro; Stimulation; T-plasminogen activator; Fibrinolysis; Activator (genetics); Pharmacology; Biochemistry; Enzyme; Biology; Receptor; Endocrinology; Cancer research; Internal medicine; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001919214,0.0001833505,0.00010272,0.00002569269,0.0002893487,0.00005873642,0.0001911768,0.0001211095,0.00005761369],"category_scores_gemma":[0.0002142658,0.0001479213,0.00009844399,0.0001058368,0.0001170327,0.00001304602,0.00006273691,0.00009695008,0.00008092975],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002550516,"about_ca_system_score_gemma":0.0004465552,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000357992,"about_ca_topic_score_gemma":0.000008611295,"domain_scores_codex":[0.9988533,0.0001057552,0.0001674352,0.0003292483,0.0002591914,0.0002851117],"domain_scores_gemma":[0.9992593,0.00004891541,0.00009692983,0.0003067616,0.00006315338,0.0002249566],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003765055,0.00002510675,0.0001284337,0.000003909844,0.00006881573,0.0000023516,0.00004682042,0.0001037686,0.9766948,0.003193398,0.01753738,0.002157554],"study_design_scores_gemma":[0.00033238,0.00007786409,0.0001924963,0.000007583173,0.000013464,0.00001324488,0.00001697465,0.0000410941,0.8251932,0.007038012,0.1669116,0.0001620728],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944221,0.0008477441,0.001913849,0.001176848,0.0003935497,0.0003257124,0.00002732532,0.00002471197,0.0008681899],"genre_scores_gemma":[0.9942223,0.00004318353,0.001888604,0.000581165,0.000458694,0.00002875813,0.00006762193,0.00002730811,0.002682353],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1515016,"threshold_uncertainty_score":0.6032056,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0133581378657629,"score_gpt":0.2450045034436959,"score_spread":0.231646365577933,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}