{"id":"W1984395407","doi":"10.1023/b:drug.0000006171.54078.3d","title":"The Antiangiogenic Agent Neovastat (Æ-941) Stimulates Tissue Plasminogen Activator Activity","year":2003,"lang":"en","type":"article","venue":"Investigational New Drugs","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université du Québec à Montréal","funders":"","keywords":"Plasmin; Plasminogen activator; Urokinase; Angiogenesis; Tissue plasminogen activator; Chemistry; In vitro; Stimulation; T-plasminogen activator; Fibrinolysis; Activator (genetics); Pharmacology; Biochemistry; Enzyme; Biology; Receptor; Endocrinology; Cancer research; Internal medicine; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001500782,0.0004208515,0.0002833293,0.0003302015,0.000132578,0.0004766863,0.0002543569,0.0003105306,0.002806414],"category_scores_gemma":[0.0002375295,0.0001911342,0.0002353305,0.0002075512,0.0002064101,0.0002800951,0.0002297197,0.0008561413,0.0008752534],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002846892,"about_ca_system_score_gemma":0.0001760166,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003209971,"about_ca_topic_score_gemma":0.0002598446,"domain_scores_codex":[0.9998524,0.00003072995,0.000007496039,0.00002035997,0.00004210617,0.00004691082],"domain_scores_gemma":[0.999891,0.00004333016,0.00002360333,0.000007259512,0.000007734405,0.00002696117],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006836165,0.0001211454,0.0003710751,0.00008210429,0.00001276012,0.0002512827,0.00001874033,0.0001117074,0.9794592,0.0006480129,0.0003462337,0.01789412],"study_design_scores_gemma":[0.0001141497,0.0008252583,0.003071754,0.000007091326,0.000014908,0.001021774,0.00001591586,0.0005026509,0.9861162,0.0001495139,0.008155034,0.000005746724],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9620827,0.02100851,0.006117177,0.0006284009,0.0001800921,0.00006524288,0.0004510934,0.000181831,0.009285008],"genre_scores_gemma":[0.9822164,0.007899136,0.003389189,0.0001807437,0.00009972539,0.00003816149,0.0006888921,0.00002602023,0.005461692],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002806414,"threshold_uncertainty_score":0.009388447,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0133581378657629,"score_gpt":0.2450045034436959,"score_spread":0.231646365577933,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}