{"id":"W1984408971","doi":"10.1097/jto.0000000000000037","title":"Randomized, Double-Blind, Phase II Trial Comparing Gemcitabine-Cisplatin plus the LTB4 Antagonist LY293111 versus Gemcitabine-Cisplatin plus Placebo in First-Line Non–Small-Cell Lung Cancer","year":2013,"lang":"en","type":"article","venue":"Journal of Thoracic Oncology","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":false,"ca_institutions":"Royal Victoria Hospital","funders":"Eli Lilly and Company","keywords":"Gemcitabine; Medicine; Placebo; Internal medicine; Lung cancer; Nausea; Cisplatin; Clinical endpoint; Randomization; Phases of clinical research; Performance status; Gastroenterology; Oncology; Chemotherapy; Randomized controlled trial; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001925162,0.0005076421,0.002278838,0.0005039665,0.0004865248,0.0001091128,0.0004275047,0.0003665006,0.0007250297],"category_scores_gemma":[0.0002597617,0.0003272334,0.0005545328,0.0005337406,0.0002647344,0.0003743769,0.0001764557,0.001295099,0.00004512936],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002536749,"about_ca_system_score_gemma":0.002359552,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001513812,"about_ca_topic_score_gemma":0.001679111,"domain_scores_codex":[0.9958211,0.0004127854,0.002047087,0.0004277525,0.0005757013,0.0007155386],"domain_scores_gemma":[0.9954586,0.001520657,0.001659701,0.0004398635,0.0005366273,0.0003845325],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9742282,0.001673264,0.0002807642,0.0001891984,0.001107944,0.0003402969,0.003261248,0.007229544,0.0003930455,0.00002644194,0.00361282,0.007657239],"study_design_scores_gemma":[0.9507303,0.004289713,0.00005676948,0.0003843844,0.003888974,0.0002237469,0.000973392,0.03533967,0.000466926,0.0000301609,0.003302642,0.0003133291],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9724293,0.001886607,0.0008323154,0.008617159,0.003764047,0.005628873,0.00002439784,0.00002990395,0.006787436],"genre_scores_gemma":[0.9909654,0.0006141544,0.001906443,0.0003103009,0.002019212,0.0008620486,0.00006227268,0.00007032088,0.003189798],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02811013,"threshold_uncertainty_score":0.999918,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0588011722106157,"score_gpt":0.4491317996074688,"score_spread":0.3903306273968531,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}