{"id":"W1984408971","doi":"10.1097/jto.0000000000000037","title":"Randomized, Double-Blind, Phase II Trial Comparing Gemcitabine-Cisplatin plus the LTB4 Antagonist LY293111 versus Gemcitabine-Cisplatin plus Placebo in First-Line Non–Small-Cell Lung Cancer","year":2013,"lang":"en","type":"article","venue":"Journal of Thoracic Oncology","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":false,"ca_institutions":"Royal Victoria Hospital","funders":"Eli Lilly and Company","keywords":"Gemcitabine; Medicine; Placebo; Internal medicine; Lung cancer; Nausea; Cisplatin; Clinical endpoint; Randomization; Phases of clinical research; Performance status; Gastroenterology; Oncology; Chemotherapy; Randomized controlled trial; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001757984,0.002159911,0.005973423,0.000489803,0.0006241894,0.001410476,0.001293853,0.002157407,0.01062929],"category_scores_gemma":[0.002142183,0.001245689,0.001955806,0.000493746,0.001801121,0.001560913,0.000593399,0.004520996,0.002124724],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001134016,"about_ca_system_score_gemma":0.001635801,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001321796,"about_ca_topic_score_gemma":0.002771385,"domain_scores_codex":[0.9993144,0.0003457771,0.00004594064,0.0001588399,0.00003849508,0.00009648936],"domain_scores_gemma":[0.9989343,0.0003131875,0.0001797372,0.0001083212,0.00007287006,0.0003915389],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9898434,0.002789455,0.0001007579,0.0003066925,0.0004298457,0.00001291063,0.00001556519,0.0001879107,0.001112903,0.00006570269,0.0004198194,0.004714981],"study_design_scores_gemma":[0.9803321,0.01870995,0.0002194024,0.00001137907,0.0001445715,0.000008745572,0.000006917282,0.000171955,0.0001293678,0.00007110857,0.0001877598,0.00000678314],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9722298,0.005646831,0.001847929,0.001573162,0.002475596,0.01005866,0.002172486,0.0004017183,0.003593819],"genre_scores_gemma":[0.9733834,0.003253291,0.002958781,0.001781031,0.000658353,0.00872231,0.001653399,0.00006923614,0.007520155],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01062929,"threshold_uncertainty_score":0.03555852,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0588011722106157,"score_gpt":0.4491317996074688,"score_spread":0.3903306273968531,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}