{"id":"W1984497969","doi":"10.1038/ng.593","title":"Lin28a transgenic mice manifest size and puberty phenotypes identified in human genetic association studies","year":2010,"lang":"en","type":"article","venue":"Nature Genetics","topic":"Plant Molecular Biology Research","field":"Agricultural and Biological Sciences","cited_by":314,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Cancer Institute; National Institutes of Health; Howard Hughes Medical Institute","keywords":"Biology; LIN28; Phenotype; Caenorhabditis elegans; Transgene; Genetics; Ribosome biogenesis; microRNA; Epigenetics; Gene; Induced pluripotent stem cell; RNA; Embryonic stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003985997,0.001053657,0.0006283108,0.00224764,0.0005222903,0.0004852352,0.0008019066,0.001359168,0.01338867],"category_scores_gemma":[0.0005533625,0.0005758486,0.0004879704,0.0006089195,0.001342979,0.0003691748,0.000831439,0.001727177,0.002018778],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002560811,"about_ca_system_score_gemma":0.0003422662,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006870682,"about_ca_topic_score_gemma":0.00142394,"domain_scores_codex":[0.9994796,0.00006900681,0.00004419355,0.0001590512,0.0001790534,0.00006910817],"domain_scores_gemma":[0.9984054,0.0003367134,0.0006401947,0.0001320572,0.00006226144,0.0004233895],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003164883,0.00008739677,0.0009424798,0.00002571034,0.00001594359,0.0009739741,0.00005437442,0.0000677659,0.9947246,0.000488925,0.0002933404,0.002009136],"study_design_scores_gemma":[0.0005762805,0.0005290895,0.09088518,0.00005131088,0.0001943555,0.02271269,0.0002868969,0.001962799,0.8636566,0.002065075,0.01698706,0.00009261547],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9724163,0.001037949,0.01362894,0.000705042,0.000322214,0.00007460795,0.00436894,0.00175014,0.005695831],"genre_scores_gemma":[0.9605698,0.0009685074,0.0115332,0.0004003267,0.0001306358,0.0002523086,0.002496946,0.001394617,0.02225362],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01338867,"threshold_uncertainty_score":0.04478955,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01441716272137425,"score_gpt":0.2786616619867575,"score_spread":0.2642444992653832,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}