{"id":"W1984503283","doi":"10.1007/s10534-014-9714-y","title":"Acute and long-term effects of arsenite in HepG2 cells: modulation of insulin signaling","year":2014,"lang":"en","type":"article","venue":"BioMetals","topic":"Heavy Metal Exposure and Toxicity","field":"Environmental Science","cited_by":30,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Arsenite; Term (time); Insulin; Modulation (music); Cell biology; Insulin receptor; Chemistry; Biology; Endocrinology; Insulin resistance; Physics; Arsenic","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003473803,0.00007940512,0.0002086069,0.00008999638,0.00001724422,0.000004029112,0.0000675494,0.00005685673,0.0000682589],"category_scores_gemma":[0.00003874925,0.00006916433,0.0000376464,0.0002961881,0.0001079946,0.00009713147,0.00008904391,0.00003224673,0.00002667407],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002157761,"about_ca_system_score_gemma":0.000002009439,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006076728,"about_ca_topic_score_gemma":0.00002760083,"domain_scores_codex":[0.9992175,0.00009223235,0.0002468797,0.0001600138,0.0001666099,0.0001167533],"domain_scores_gemma":[0.9995945,0.0001106656,0.0001124599,0.0001298453,0.000004143314,0.00004836935],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001361596,0.00005291096,0.05667773,0.00005588947,0.00001075453,0.000002192038,0.0001022837,0.0000600506,0.9335252,0.000007568088,0.000001719641,0.009490097],"study_design_scores_gemma":[0.0002294282,0.00007691198,0.3823159,0.0000181217,0.00001218103,8.579127e-7,7.170032e-7,0.0004313116,0.6167758,0.00007226642,0.0000184842,0.00004805058],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989545,0.00007616007,0.0005558422,0.00000720801,0.00004864007,0.0001492957,0.000003890182,0.000005775006,0.0001986558],"genre_scores_gemma":[0.9992147,0.00002601273,0.0006543121,0.00001878968,0.000009387004,0.000003075999,0.00000303529,0.00000572627,0.00006497672],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3256382,"threshold_uncertainty_score":0.2820439,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008571426852600122,"score_gpt":0.2324221368613804,"score_spread":0.2238507100087803,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}