{"id":"W1984508540","doi":"10.1021/bi0363073","title":"Molecular Determinants of Heritable Vitamin E Deficiency","year":2004,"lang":"en","type":"article","venue":"Biochemistry","topic":"Antioxidant Activity and Oxidative Stress","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brock University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Tocopherol; Chemistry; Mutant; Vitamin E deficiency; Biochemistry; Missense mutation; In vivo; In vitro; Phospholipid transfer protein; Recombinant DNA; Biology; Cell biology; Vitamin E; Mutation; Genetics; Gene; Phospholipid; Membrane","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005898267,0.000466299,0.0001970394,0.0004912796,0.0001215163,0.0001641997,0.0002018067,0.0003952702,0.003763638],"category_scores_gemma":[0.0004106439,0.0001067125,0.0001982458,0.0002375256,0.0002595645,0.0001095113,0.000388517,0.0002959977,0.0004951934],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001419687,"about_ca_system_score_gemma":0.00007391423,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003841534,"about_ca_topic_score_gemma":0.0002037121,"domain_scores_codex":[0.9998617,0.00002546185,0.00001823198,0.0000405994,0.00003339618,0.00002054644],"domain_scores_gemma":[0.9996909,0.00006730463,0.0001344369,0.00002969233,0.00001812831,0.00005963349],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004061604,0.00005665267,0.01437474,0.00004025222,0.00003148238,0.005177394,0.00004918165,0.0001196572,0.9749743,0.0004902298,0.0001237337,0.004156154],"study_design_scores_gemma":[0.00008189941,0.001074038,0.4753787,0.00003819578,0.0001521904,0.07386909,0.0001830663,0.001976695,0.4390398,0.0006677166,0.007494864,0.00004374968],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967375,0.0005175694,0.0009260357,0.0000658528,0.0000160699,0.00001706305,0.0004233214,0.0000719367,0.001224712],"genre_scores_gemma":[0.9985287,0.000216323,0.000376766,0.00001346311,0.00001069919,0.000006398855,0.0002897685,0.00001364531,0.0005441447],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003763638,"threshold_uncertainty_score":0.01259065,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01022679305027606,"score_gpt":0.2656298619991735,"score_spread":0.2554030689488975,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}