{"id":"W1984508540","doi":"10.1021/bi0363073","title":"Molecular Determinants of Heritable Vitamin E Deficiency","year":2004,"lang":"en","type":"article","venue":"Biochemistry","topic":"Antioxidant Activity and Oxidative Stress","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brock University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Tocopherol; Chemistry; Mutant; Vitamin E deficiency; Biochemistry; Missense mutation; In vivo; In vitro; Phospholipid transfer protein; Recombinant DNA; Biology; Cell biology; Vitamin E; Mutation; Genetics; Gene; Phospholipid; Membrane","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004503408,0.00008961291,0.0001726501,0.00002038004,0.00002537029,0.00000362847,0.0000670153,0.00008134425,0.00003329595],"category_scores_gemma":[0.0000727692,0.0000838817,0.00006881355,0.0001126125,0.0001117816,0.00003394322,0.00002966246,0.00007471552,0.000008818072],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003277299,"about_ca_system_score_gemma":0.0001091333,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002619557,"about_ca_topic_score_gemma":9.76514e-7,"domain_scores_codex":[0.9993998,0.000004396686,0.0001343857,0.0001626215,0.0001472716,0.0001515697],"domain_scores_gemma":[0.9996052,0.000008738157,0.00006246805,0.0002066956,0.00005418928,0.00006275358],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003160082,0.0002095894,0.01045304,0.0002363443,0.000007344508,0.00006695676,0.00002879089,0.000002990701,0.988031,0.00005764347,0.00001720229,0.0008574513],"study_design_scores_gemma":[0.0006598124,0.00007313854,0.00923205,0.0001793056,0.00002580142,0.00006303679,0.0001168534,0.000006901766,0.9894686,0.0000646065,0.00002715121,0.00008270279],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931233,0.000344624,0.0004018648,0.00005857766,0.00002248957,0.00006606536,0.00001114744,0.00002016082,0.005951757],"genre_scores_gemma":[0.9986439,0.00001652859,0.0009811852,0.00003651284,0.00002265179,0.0000032515,0.000006771961,0.000008855052,0.0002802894],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005671467,"threshold_uncertainty_score":0.3420596,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01022679305027606,"score_gpt":0.2656298619991735,"score_spread":0.2554030689488975,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}