{"id":"W1984526102","doi":"10.2350/14-07-1525-cr.1","title":"Fatal Congenital Hypertrophic Cardiomyopathy and a Pancreatic Nodule Morphologically Identical to Focal Lesion of Congenital Hyperinsulinism in an Infant with Costello Syndrome: Case Report and Review of the Literature","year":2015,"lang":"en","type":"review","venue":"Pediatric and Developmental Pathology","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; Child and Family Research Institute; Children's & Women's Health Centre of British Columbia; University of British Columbia","funders":"","keywords":"Congenital hyperinsulinism; Costello syndrome; HRAS; Hyperinsulinism; Medicine; Hypertrophic cardiomyopathy; Pathology; Hypoglycemia; Noonan syndrome; Internal medicine; Insulin; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003029136,0.0008480509,0.001513459,0.004057663,0.0002930933,0.0007731064,0.000871049,0.001005598,0.001440351],"category_scores_gemma":[0.0007068962,0.0002572302,0.0004084308,0.00263178,0.0005903465,0.001307696,0.0005717269,0.0008488039,0.0008757772],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003361837,"about_ca_system_score_gemma":0.0007759173,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007289123,"about_ca_topic_score_gemma":0.001327283,"domain_scores_codex":[0.9998029,0.00002221122,0.00006102492,0.00003966425,0.00005492612,0.00001927849],"domain_scores_gemma":[0.9996386,0.0001444843,0.00009976107,0.00001177906,0.00005264178,0.00005274601],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"case_report","study_design_scores_codex":[0.0001074866,0.00009881578,0.003489258,0.02538897,0.0002733009,0.05451852,0.0002575247,0.0004866765,0.003504081,0.001575792,0.03178485,0.8785148],"study_design_scores_gemma":[0.00003712919,0.000174743,0.01197698,0.007205203,0.0006231514,0.5596529,0.0004370966,0.0002478032,0.001334482,0.001782219,0.416428,0.0001001972],"study_design_candidate":"case_report","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001270857,0.997454,0.0001640545,0.0001909557,0.000146153,0.000005570363,0.00002413438,0.0000110435,0.0007332558],"genre_scores_gemma":[0.006330123,0.9922979,0.0003208759,0.0002610868,0.0003557169,0.000006074255,0.00006105981,0.000003785803,0.000363363],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004057663,"threshold_uncertainty_score":0.004818439,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01922502845593864,"score_gpt":0.2767199721540485,"score_spread":0.2574949436981098,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}