{"id":"W1984532367","doi":"10.1159/000130452","title":"A quantitative analysis of Colcemid-induced chromosomal nondisjunction in Chinese hamster cells in vitro","year":2008,"lang":"en","type":"article","venue":"Cytogenetics and Cell Genetics","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Children's Hospital of Winnipeg","funders":"","keywords":"Nondisjunction; Colcemid; Biology; Monosomy; Chinese hamster; Genetics; Aneuploidy; Chromosome; Chromosome 21; Trisomy; Molecular biology; Karyotype; In vitro; Cell culture; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007025115,0.0009141157,0.0006354882,0.001556096,0.0005523578,0.0004528815,0.0004894424,0.0003404337,0.002200482],"category_scores_gemma":[0.0005891765,0.0004596289,0.0005604041,0.0009751674,0.000469877,0.0002875597,0.0004443158,0.001131458,0.0006392822],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009913038,"about_ca_system_score_gemma":0.0006086575,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00346165,"about_ca_topic_score_gemma":0.003825574,"domain_scores_codex":[0.9990696,0.0002408411,0.00008271889,0.0001237686,0.0003997333,0.00008326468],"domain_scores_gemma":[0.9987613,0.0004390963,0.0001818221,0.0002125274,0.0002758478,0.0001294154],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002651056,0.00001171345,0.0001112449,0.00004828071,0.000005922502,0.00001791542,0.00003044768,0.00004380579,0.9989507,0.00005330765,0.0000107156,0.0006893104],"study_design_scores_gemma":[0.000004805522,0.0001930328,0.007739878,0.000007529351,0.00001969035,0.00008305641,0.00003297344,0.0006937287,0.9900816,0.00004133217,0.001092405,0.000009868926],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9391293,0.008003511,0.04259672,0.0001048942,0.00009476147,0.0003742649,0.002319189,0.0005221249,0.006855376],"genre_scores_gemma":[0.9273977,0.00445455,0.04006944,0.00008173007,0.00004801704,0.0008174184,0.005370788,0.0002674018,0.02149301],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00346165,"threshold_uncertainty_score":0.007361352,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01453868561624883,"score_gpt":0.2478773161166508,"score_spread":0.2333386305004019,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}