{"id":"W1984538871","doi":"10.1073/pnas.1010689108","title":"Structure of betaglycan zona pellucida (ZP)-C domain provides insights into ZP-mediated protein polymerization and TGF-β binding","year":2011,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; Canadian Institutes of Health Research; National Institutes of Health; Northwestern University","keywords":"Zona pellucida; Immunoglobulin domain; Cell biology; Cleavage (geology); Chemistry; Endoglin; Extracellular matrix; Extracellular; Biology; Biochemistry; Receptor; Oocyte; Embryo","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004104958,0.0002402401,0.0001536951,0.0001279338,0.0002432593,0.0002599395,0.000301247,0.0002791601,0.001498599],"category_scores_gemma":[0.00009277424,0.0001038871,0.0001981286,0.0001497694,0.0001629005,0.0002043578,0.000156109,0.0005164332,0.0003123575],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005290035,"about_ca_system_score_gemma":0.0005011014,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004221489,"about_ca_topic_score_gemma":0.00369772,"domain_scores_codex":[0.9999768,0.000002532646,7.658389e-7,0.000004825166,0.00000970267,0.00000555962],"domain_scores_gemma":[0.9999745,0.000003238517,0.000005609152,0.000001667586,0.000004449922,0.00001056963],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001321175,0.00005551224,0.002683323,0.0001284653,0.00002057325,0.0006647923,0.00008390856,0.001854618,0.9824156,0.002590982,0.001104238,0.008265757],"study_design_scores_gemma":[0.0001770419,0.0003984655,0.1115544,0.0001146219,0.0001497325,0.003404586,0.0005124289,0.0808747,0.7154218,0.00384141,0.08346724,0.00008355157],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9760041,0.005690891,0.007273684,0.0007228872,0.0000522236,0.00002854337,0.0005115534,0.0001813444,0.009534772],"genre_scores_gemma":[0.9842923,0.002555347,0.007494726,0.0001519926,0.00001683216,0.0000129032,0.001330245,0.00002056603,0.004125159],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004221489,"threshold_uncertainty_score":0.008393884,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03333047452726765,"score_gpt":0.2914761505432275,"score_spread":0.2581456760159598,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}