{"id":"W1984554756","doi":"10.1007/s00439-014-1455-z","title":"Opposite effects on facial morphology due to gene dosage sensitivity","year":2014,"lang":"en","type":"article","venue":"Human Genetics","topic":"Genomic variations and chromosomal abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Children's Hospital of Eastern Ontario","funders":"National Institute on Alcohol Abuse and Alcoholism","keywords":"Biology; Human genetics; Morphology (biology); Gene; Sensitivity (control systems); Genetics; Gene dosage; Evolutionary biology; Computational biology; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001679702,0.0001858621,0.0001755513,0.00005058045,0.0001834057,0.0000326882,0.0001327637,0.0001518762,0.00002399572],"category_scores_gemma":[0.00003262095,0.0001931703,0.00007469918,0.00004510159,0.00004134805,0.00000130141,0.0001500995,0.00007595361,0.0001153136],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001626935,"about_ca_system_score_gemma":0.00002108755,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001688528,"about_ca_topic_score_gemma":0.00005862731,"domain_scores_codex":[0.9989112,0.000160924,0.0001679733,0.0003621528,0.0001043045,0.0002934667],"domain_scores_gemma":[0.9993153,0.00002026176,0.0000504629,0.0004332517,0.00005311006,0.0001276644],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002715024,0.00004688407,0.001516041,0.0000141068,0.00002952138,0.00001959269,0.0001032521,0.0006873372,0.9931577,0.0004973878,0.0009623659,0.002938664],"study_design_scores_gemma":[0.0004807935,0.00103329,0.0502857,0.000007106918,0.00002420153,0.00006402014,0.00001217158,0.00005317,0.9279698,0.000183525,0.01959311,0.0002931796],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931487,0.00005211227,0.004586288,0.0001037032,0.0002294434,0.0001948098,0.00003501841,0.00001830388,0.001631582],"genre_scores_gemma":[0.9953746,0.000009863619,0.001515166,0.001309065,0.0008137221,0.0000208423,0.000136146,0.00002830001,0.0007922691],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06518797,"threshold_uncertainty_score":0.7877257,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00811129034417643,"score_gpt":0.2269955493057866,"score_spread":0.2188842589616102,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}