{"id":"W1984559762","doi":"10.1016/j.biochi.2013.01.013","title":"Lessons in biology from patients with inborn errors of vitamin B12 metabolism","year":2013,"lang":"en","type":"review","venue":"Biochimie","topic":"Folate and B Vitamins Research","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; McGill Genome Centre","funders":"Canadian Institutes of Health Research; McGill University","keywords":"Methylcobalamin; Adenosylcobalamin; Vitamin B12; Methionine synthase; Mutase; Biochemistry; Metabolism; Methylmalonic acid; Homocysteine; Methylmalonic acidemia; Complementation; Cyanocobalamin; Hydroxocobalamin; Biology; Chemistry; Cobalamin; Methionine; Endocrinology; Gene; Amino acid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009523387,0.0007930339,0.001568717,0.001745616,0.0002586083,0.001113938,0.000784361,0.001512019,0.002170562],"category_scores_gemma":[0.00203672,0.0001951065,0.0005023283,0.001596537,0.0008444287,0.001458955,0.0008378732,0.002175831,0.001111629],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008320632,"about_ca_system_score_gemma":0.001066145,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001475113,"about_ca_topic_score_gemma":0.002552402,"domain_scores_codex":[0.9997433,0.00005464391,0.00004777025,0.00004951334,0.0000810761,0.00002373362],"domain_scores_gemma":[0.9992762,0.0004354632,0.00005632143,0.00002287235,0.0001639521,0.00004514273],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001503016,0.00005433012,0.001168984,0.009731887,0.0001965615,0.0009822943,0.0001021747,0.0001826965,0.001153631,0.006678254,0.05449845,0.9251003],"study_design_scores_gemma":[0.00003841173,0.00004996636,0.001534877,0.004722775,0.0001893682,0.004228859,0.0001473142,0.00007027804,0.000620753,0.007690131,0.9806808,0.00002659929],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001024254,0.9978136,0.0001375438,0.001179473,0.0003023907,9.91338e-7,0.00001504433,0.000004738302,0.0004438047],"genre_scores_gemma":[0.001121366,0.996768,0.0002793479,0.0007672136,0.0006119251,0.000002524362,0.00002366723,0.000001878568,0.0004241217],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002170562,"threshold_uncertainty_score":0.007261276,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06283927062462612,"score_gpt":0.3821320787152046,"score_spread":0.3192928080905785,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}