{"id":"W1984559762","doi":"10.1016/j.biochi.2013.01.013","title":"Lessons in biology from patients with inborn errors of vitamin B12 metabolism","year":2013,"lang":"en","type":"review","venue":"Biochimie","topic":"Folate and B Vitamins Research","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; McGill Genome Centre","funders":"Canadian Institutes of Health Research; McGill University","keywords":"Methylcobalamin; Adenosylcobalamin; Vitamin B12; Methionine synthase; Mutase; Biochemistry; Metabolism; Methylmalonic acid; Homocysteine; Methylmalonic acidemia; Complementation; Cyanocobalamin; Hydroxocobalamin; Biology; Chemistry; Cobalamin; Methionine; Endocrinology; Gene; Amino acid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001566264,0.0003961091,0.002189343,0.0006217859,0.00002219959,0.000009139517,0.0002963491,0.0005219316,0.0003017682],"category_scores_gemma":[0.0001258826,0.0002384698,0.0002510982,0.0006101694,0.0001894353,0.00004644646,0.0001535556,0.0005746721,0.0002064521],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008588195,"about_ca_system_score_gemma":0.0004111176,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001003301,"about_ca_topic_score_gemma":0.0001074206,"domain_scores_codex":[0.9979278,0.0002024376,0.0006221457,0.0005269082,0.0003037587,0.0004169943],"domain_scores_gemma":[0.9986421,0.000161799,0.0002669352,0.0006321265,0.0001406449,0.0001563367],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005652384,0.0006665824,0.001594498,0.004140495,0.0005347604,0.00001747947,0.00005608334,2.176155e-8,0.00004813162,0.00008864489,0.00124582,0.991551],"study_design_scores_gemma":[0.001961525,0.0005070758,0.01348789,0.008118241,0.00092056,0.000003461341,0.00001939365,0.000001406057,0.00007166784,0.00002355848,0.9745125,0.0003726952],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03069333,0.9665386,0.000002992552,0.00006932618,0.000205911,0.001418663,0.0005295741,0.00001811046,0.0005234753],"genre_scores_gemma":[0.002525497,0.9943307,0.0005319234,0.00002784743,0.0001201991,0.0001363555,0.001734814,0.00006779034,0.0005248619],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9911783,"threshold_uncertainty_score":0.9724516,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06283927062462612,"score_gpt":0.3821320787152046,"score_spread":0.3192928080905785,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}