{"id":"W1984570318","doi":"10.1074/jbc.m111.311605","title":"Ligand-dependent Corepressor (LCoR) Recruitment by Krüppel-like Factor 6 (KLF6) Regulates Expression of the Cyclin-dependent Kinase Inhibitor CDKN1A Gene","year":2012,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Kruppel-like factors research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; McGill University","funders":"Canadian Institutes of Health Research","keywords":"Corepressor; Trichostatin A; Biology; Promoter; Transactivation; Transcription factor; Psychological repression; Molecular biology; Cell biology; Repressor; Cancer research; Histone deacetylase; Gene; Gene expression; Histone; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006528826,0.0003615305,0.000497214,0.00003197724,0.0001145787,0.00003452491,0.0008878387,0.0006452033,0.0001853438],"category_scores_gemma":[0.000569335,0.0002102395,0.0004445717,0.0001060153,0.0002779923,0.00001920093,0.0007031438,0.0005931347,0.000006340643],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001129807,"about_ca_system_score_gemma":0.0001257891,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005166189,"about_ca_topic_score_gemma":5.463676e-7,"domain_scores_codex":[0.9971125,0.0002153794,0.0009192098,0.0004044439,0.0007293609,0.0006191556],"domain_scores_gemma":[0.9976385,0.00009195409,0.0008594751,0.0006701432,0.0003179804,0.0004219013],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000471448,0.0005637768,0.02969595,0.00004407179,0.00008690497,0.000008061451,0.00004147182,0.00001011506,0.9656889,4.642029e-7,0.002805934,0.0005828657],"study_design_scores_gemma":[0.000955564,0.0003353324,0.005676406,0.00008077208,0.00002769856,0.0001250513,0.0001361804,0.000001542817,0.9864627,0.00001911615,0.005924239,0.0002554065],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943429,0.004240599,0.00006600843,0.0001490566,0.0004704074,0.0003237254,0.0001931718,0.000009231829,0.0002049211],"genre_scores_gemma":[0.9967303,0.0008197574,0.000196577,0.00008944039,0.0008306506,0.00002035343,0.00006002288,0.00003025999,0.00122259],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02401954,"threshold_uncertainty_score":0.8573319,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04566145574647177,"score_gpt":0.3034161969170661,"score_spread":0.2577547411705943,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}