{"id":"W1984600220","doi":"10.1002/pmic.200800914","title":"Proteomic profiling of the prechylomicron transport vesicle involved in the assembly and secretion of apoB‐48‐containing chylomicrons in the intestinal enterocytes","year":2009,"lang":"en","type":"article","venue":"PROTEOMICS","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hamilton Regional Laboratory Medicine Program; Hamilton Health Sciences; Hospital for Sick Children; McMaster University; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Vesicular transport protein; Chylomicron; Cell biology; Secretion; Transport protein; Intracellular; Golgi apparatus; COPI; Vesicle; Biology; Rab; Vesicular Transport Proteins; Biochemistry; Microsomal triglyceride transfer protein; Intracellular transport; Secretory pathway; Endosome; Lipoprotein; Endoplasmic reticulum; Very low-density lipoprotein; Cholesterol; Membrane; GTPase","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005248462,0.0001343277,0.0001534745,0.00003381008,0.00004859429,0.00001524671,0.0003394068,0.00008211601,5.745937e-7],"category_scores_gemma":[0.0001075008,0.00007863213,0.00007233388,0.0001102231,0.0001151175,0.000008593438,0.00003674818,0.0001805503,1.249508e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001448795,"about_ca_system_score_gemma":0.00008282585,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006467774,"about_ca_topic_score_gemma":0.00007688869,"domain_scores_codex":[0.9989907,0.000164079,0.000337514,0.0002123088,0.0001148775,0.0001804975],"domain_scores_gemma":[0.999458,0.00002315204,0.0001787488,0.0002856456,0.00003414616,0.00002028488],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002778975,0.0001065004,0.1365372,0.00005569603,0.000006390143,0.000001287211,0.0007428027,0.0000756891,0.8616753,0.0001731094,0.000004204298,0.0003438974],"study_design_scores_gemma":[0.0008325953,0.0002389549,0.1408445,0.0001204686,0.00001926742,0.000008988703,0.0006935991,0.0004161457,0.8563883,0.0003345379,0.00001094737,0.00009167725],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997618,0.0003170177,0.0003118834,0.0003099295,0.00002037721,0.001285397,0.00001438876,0.000002772106,0.0001202355],"genre_scores_gemma":[0.9984296,0.00008019343,0.001189834,0.000137244,0.00003215905,0.00009609654,0.00002376917,0.000008059379,0.000003045569],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005287019,"threshold_uncertainty_score":0.3206525,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009735084345220569,"score_gpt":0.2383073834587908,"score_spread":0.2285722991135702,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}