{"id":"W1984610422","doi":"10.1371/journal.pone.0096448","title":"Development of a Curved, Stratified, In Vitro Model to Assess Ocular Biocompatibility","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Ocular Surface and Contact Lens","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biocompatibility; Viability assay; Flow cytometry; Benzalkonium chloride; Corneal epithelium; Cornea; Cytotoxicity; Chemistry; Biophysics; Biomedical engineering; In vitro; Materials science; Molecular biology; Medicine; Biology; Ophthalmology; Biochemistry; Chromatography","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003996487,0.0001074126,0.0003888299,0.0000815295,0.00001928155,0.000006428681,0.00008032319,0.00005919347,0.00002039821],"category_scores_gemma":[0.0001033979,0.00009975995,0.00004135992,0.0001462715,0.0000133367,0.00004240402,0.00003867916,0.000117602,0.00003276419],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006057001,"about_ca_system_score_gemma":0.000154022,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003608625,"about_ca_topic_score_gemma":0.0001271408,"domain_scores_codex":[0.9988586,0.00004100712,0.0003328601,0.0002257934,0.0003573825,0.0001843807],"domain_scores_gemma":[0.9993306,0.0000262292,0.00004877019,0.0003732014,0.0001067701,0.000114393],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002025532,0.002138497,0.0413356,0.0002832061,0.0000995397,0.000002692687,0.0006437998,0.00006116043,0.9528294,0.000106149,0.00000190715,0.002295495],"study_design_scores_gemma":[0.0009485338,0.00009766722,0.03550689,0.0002582851,0.00006009864,1.313265e-7,0.00008234416,0.02322587,0.9395602,0.000084564,0.00004489263,0.0001304638],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927346,0.00002694825,0.005699552,0.0002010682,0.000007623144,0.0004674698,0.000003980758,0.00002287143,0.0008358614],"genre_scores_gemma":[0.8947481,0.000001719987,0.1049263,0.0001728127,0.00001271885,0.0000249998,0.00001490502,0.00001118439,0.00008720467],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09922678,"threshold_uncertainty_score":0.4068093,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1111836531137193,"score_gpt":0.2884805726782913,"score_spread":0.177296919564572,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}