{"id":"W1984695081","doi":"10.1152/ajpregu.00137.2010","title":"Cortactin activation by FVIIa/tissue factor and PAR2 promotes endothelial cell migration","year":2010,"lang":"en","type":"article","venue":"American Journal of Physiology-Regulatory, Integrative and Comparative Physiology","topic":"Blood Coagulation and Thrombosis Mechanisms","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"","keywords":"Cortactin; Cell biology; RHOA; Cell migration; Lamellipodium; Tissue factor; Downregulation and upregulation; Chemistry; Gene silencing; Biology; Cell; Signal transduction; Coagulation; Biochemistry; Cytoskeleton; Internal medicine; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007168621,0.0002189169,0.0001114105,0.0001359511,0.000122004,0.0002160553,0.00007703863,0.0001425169,0.0009794505],"category_scores_gemma":[0.0000602803,0.00007705641,0.0001586781,0.00006149618,0.0001113388,0.0000997325,0.0001155674,0.0003187894,0.0002672251],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000231363,"about_ca_system_score_gemma":0.0001227063,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008561079,"about_ca_topic_score_gemma":0.0009564347,"domain_scores_codex":[0.9998993,0.00002146121,0.00000420444,0.00001899321,0.00002014291,0.00003595019],"domain_scores_gemma":[0.9999663,0.000003702545,0.000008442441,0.000003578841,0.000004884056,0.00001305816],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004764989,0.000006846599,0.00006060307,0.00001403383,0.000002188805,0.00003005831,0.000006795651,0.00002006616,0.9991816,0.00005470407,0.00005732477,0.0005182209],"study_design_scores_gemma":[0.00002298721,0.0002268097,0.01523021,0.000006478093,0.00001409946,0.0003811885,0.0000492232,0.001942439,0.9770048,0.00006757439,0.00504854,0.000005685628],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925332,0.001823453,0.002260844,0.0001165523,0.0000294459,0.0000189545,0.0001781715,0.0001132504,0.002926086],"genre_scores_gemma":[0.996588,0.0004830178,0.0009569318,0.00003696434,0.000009726811,0.00002214497,0.0001534738,0.000009946029,0.001739766],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009794505,"threshold_uncertainty_score":0.003276587,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01996624930038593,"score_gpt":0.2915236800013815,"score_spread":0.2715574307009955,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}