{"id":"W1984705156","doi":"10.1002/jcp.22520","title":"Decreased secretion of MMP by non-lesional late-stage scleroderma fibroblasts after selection via activation of the apoptotic fas-pathway","year":2010,"lang":"en","type":"article","venue":"Journal of Cellular Physiology","topic":"Systemic Sclerosis and Related Diseases","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; Centre hospitalier de l'Université Laval; Hôpital Notre-Dame; Centre hospitalier universitaire de Québec; Université de Montréal; Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Apoptosis; Fibroblast; Biology; Fibrosis; Matrix metalloproteinase; Secretion; Phenotype; Pathology; Cell; Cancer research; Immunology; Medicine; Cell culture; Endocrinology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002322588,0.0001336628,0.0003979432,0.000117637,0.00004358192,0.000003772268,0.0001089827,0.0002371623,0.0002990112],"category_scores_gemma":[0.00009282939,0.00008306685,0.0002843534,0.0001873151,0.0001209391,0.00009197061,0.00002442505,0.0003775895,0.000003220447],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003412368,"about_ca_system_score_gemma":0.0002022388,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002586545,"about_ca_topic_score_gemma":0.000001063586,"domain_scores_codex":[0.9986346,0.0001423465,0.0006213805,0.0001327337,0.0003242787,0.0001446259],"domain_scores_gemma":[0.9983346,0.00009042949,0.0009074835,0.0001814513,0.0003806769,0.0001053968],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008465894,0.0003016186,0.002395651,0.0001405486,0.0001112336,0.00000113068,0.00008245248,0.0002458608,0.9953548,0.000008880799,0.0001748917,0.0003362962],"study_design_scores_gemma":[0.001331541,0.0003454913,0.1689212,0.0005429312,0.0001086512,0.00002289568,0.00003493319,0.002209814,0.8262759,0.00005799038,0.00008140242,0.00006718867],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981291,0.0001152101,0.001000512,0.0001003418,0.0003822024,0.0001928032,0.000007974199,0.000004885439,0.00006696345],"genre_scores_gemma":[0.9994113,0.000033135,0.0001079911,0.00007302541,0.0002270719,0.000003496807,0.00002017062,0.00001685196,0.0001069856],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1690789,"threshold_uncertainty_score":0.3387368,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00536461490927333,"score_gpt":0.2069982399888169,"score_spread":0.2016336250795435,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}