{"id":"W1984726811","doi":"10.1001/jamadermatol.2014.61","title":"Primary Systemic (Amyloid Light-Chain) Amyloidosis Masquerading as Pseudoxanthoma Elasticum","year":2014,"lang":"en","type":"article","venue":"JAMA Dermatology","topic":"Dermatological and Skeletal Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Medicine; Amyloidosis; Macroglossia; Pathology; Primary systemic amyloidosis; Amyloid (mycology); Papillary dermis; Pseudoxanthoma elasticum; Pathological; AL amyloidosis; Dermatology; Systemic disease; Dermis; Tongue; Disease; Immunoglobulin light chain","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001648541,0.0003836054,0.0005619886,0.000116198,0.0001991201,0.00007650098,0.0004804943,0.0006257074,0.0000816357],"category_scores_gemma":[0.0003359832,0.0003318825,0.0002344968,0.0001677333,0.0001744967,0.00001581342,0.0002567212,0.000263109,0.0004907401],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002342069,"about_ca_system_score_gemma":0.00005930901,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001215941,"about_ca_topic_score_gemma":0.000007723165,"domain_scores_codex":[0.9975196,0.0003513274,0.0005390341,0.0006907681,0.0002103489,0.0006889768],"domain_scores_gemma":[0.9988538,0.00009192404,0.0001862694,0.0005418874,0.00009817562,0.0002279331],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003174985,0.0002997079,0.027301,0.0005390641,0.0002609937,0.0002603356,0.0001372913,0.00005668271,0.8991154,0.01638264,0.04701977,0.008309575],"study_design_scores_gemma":[0.005936304,0.0009102555,0.01853346,0.0002239577,0.0002045035,0.02711609,0.0004932392,0.001564319,0.2739406,0.005621952,0.6629208,0.002534498],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.939252,0.001234166,0.004905742,0.003701355,0.0005187386,0.0002938399,0.000008705772,0.0001163777,0.04996904],"genre_scores_gemma":[0.9932479,0.000232435,0.00037173,0.004778555,0.0002118091,0.00007787105,0.0001355373,0.00004683307,0.0008973333],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6251748,"threshold_uncertainty_score":0.9999133,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003897370641366253,"score_gpt":0.20370509417529,"score_spread":0.1998077235339238,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}