{"id":"W1984735835","doi":"10.1186/2045-8118-9-10","title":"Blood–brain barrier disruption in CCL2 transgenic mice during pertussis toxin-induced brain inflammation","year":2012,"lang":"en","type":"article","venue":"Fluids and Barriers of the CNS","topic":"Barrier Structure and Function Studies","field":"Neuroscience","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital; University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Inflammation; Blood–brain barrier; Pertussis toxin; Neurology; Medicine; Genetically modified mouse; Transgene; Neuroinflammation; Hematology; Toxin; Immunology; Neuroscience; Pathology; Internal medicine; Biology; Central nervous system; Microbiology; Receptor; Biochemistry; Gene; G protein","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003228207,0.0001912528,0.0002305862,0.0001169051,0.0003763048,0.00003062197,0.0001907687,0.0001151474,0.00008881803],"category_scores_gemma":[0.0008800855,0.0001354674,0.0001158037,0.0003638924,0.0001749506,0.0004029793,0.00009121807,0.0002044467,0.000003246919],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002931834,"about_ca_system_score_gemma":0.00003156092,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002713889,"about_ca_topic_score_gemma":0.00003445712,"domain_scores_codex":[0.9985809,0.000198923,0.0003310741,0.0002763534,0.0002534033,0.0003593635],"domain_scores_gemma":[0.9992884,0.0001709799,0.00009369555,0.0002614581,0.00002433984,0.0001611252],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005478513,0.00001207952,0.01124114,0.00003769646,0.00001560496,4.952502e-7,0.005455649,0.000003969428,0.981506,0.0006843124,0.0002155343,0.000772756],"study_design_scores_gemma":[0.001050669,0.00005855411,0.08104987,0.00004283669,0.00005453247,0.00002281035,0.0009211951,0.00005314085,0.9137823,0.000291024,0.002442215,0.0002308577],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950448,0.0002183108,0.00003587024,0.003043168,0.0006713807,0.0002391149,0.00002745887,0.00003104337,0.0006889024],"genre_scores_gemma":[0.9984985,0.00004917544,0.00002615424,0.0005852467,0.0002449649,0.00002129265,0.000001021426,0.00001751631,0.0005561201],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06980873,"threshold_uncertainty_score":0.5524199,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01562250285384173,"score_gpt":0.2391827417648434,"score_spread":0.2235602389110017,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}