{"id":"W1984788964","doi":"10.1016/j.molmed.2003.09.006","title":"Slipping while sleeping? Trinucleotide repeat expansions in germ cells","year":2003,"lang":"en","type":"review","venue":"Trends in Molecular Medicine","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":79,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children","funders":"","keywords":"Biology; Meiosis; Ploidy; Germ cell; Genetics; Trinucleotide repeat expansion; Disease; Mutation; Germ; Germline mosaicism; Allele; Cell biology; Medicine; Pathology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004462306,0.0008265427,0.002231516,0.001930304,0.00007640727,0.00002468372,0.0007611098,0.0002479992,0.0006257857],"category_scores_gemma":[0.0009730771,0.0007110172,0.0003985936,0.003118995,0.0002901341,0.0000474541,0.0001797523,0.0008852181,0.00006771527],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002088423,"about_ca_system_score_gemma":0.0001784437,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002307088,"about_ca_topic_score_gemma":0.0000198319,"domain_scores_codex":[0.9937091,0.001661571,0.001421822,0.001656414,0.0007437414,0.0008073545],"domain_scores_gemma":[0.9975423,0.0004158225,0.0004390216,0.001277591,0.00003312798,0.0002921134],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001173623,0.0003284407,0.000009502912,0.002683352,0.00002522045,0.004819062,0.0003550731,0.0002135486,0.05323071,0.0004174715,0.002465641,0.9354402],"study_design_scores_gemma":[0.002069707,0.0002808018,0.00003545509,0.01854029,0.0005586995,0.0001659604,0.00005184922,0.00006167716,0.03155898,0.0000903675,0.9452186,0.001367577],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001751683,0.9887438,0.0001101251,0.0001353474,0.0009591233,0.0007399374,0.00005069414,0.00007655344,0.007432761],"genre_scores_gemma":[0.001652392,0.9950688,0.0002257356,0.001284559,0.0001180728,0.0002339042,0.00007012984,0.0001694299,0.00117694],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.942753,"threshold_uncertainty_score":0.9995341,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08106154913628881,"score_gpt":0.3557150828711896,"score_spread":0.2746535337349008,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}