{"id":"W1984795661","doi":"10.1038/nature01150","title":"Establishment of transcriptional competence in early and late S phase","year":2002,"lang":"en","type":"article","venue":"Nature","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":169,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto General Hospital","funders":"","keywords":"Biology; DNA replication; Chromatin; Epigenetics; Origin recognition complex; Gene; Pre-replication complex; DNA; Licensing factor; Genetics; Control of chromosome duplication; Transcription (linguistics); Cell biology; Eukaryotic DNA replication; Histone; Housekeeping gene; Cell cycle; Cell division; Gene expression; Cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003602609,0.00004817747,0.00005685155,0.00001859223,0.00001063266,0.000006030002,0.00005730842,0.0002461951,0.00001421636],"category_scores_gemma":[0.000005993565,0.00004655367,0.00001854583,0.00003428873,0.00002594049,0.000001603732,0.00001505365,0.0001870246,5.001577e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003480773,"about_ca_system_score_gemma":0.000005144582,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004340294,"about_ca_topic_score_gemma":0.00001774397,"domain_scores_codex":[0.9996871,0.000007722353,0.00007993462,0.0001058751,0.0000505883,0.00006877533],"domain_scores_gemma":[0.9998566,0.000002312755,0.00002320887,0.00007668086,0.00002011856,0.00002110473],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00002442648,0.0001317875,0.004453031,0.00001962401,0.00001143048,0.000002871139,0.0001458457,0.0000589097,0.9922956,0.0006768249,0.0001529098,0.002026704],"study_design_scores_gemma":[0.01669243,0.002494703,0.6547508,0.0001656554,0.00006554397,0.00007981012,0.0002219695,0.03465087,0.2012849,0.002555085,0.08581159,0.001226644],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970151,0.002174399,0.00003312789,0.0001212507,0.00003975508,0.0000466273,0.00003341528,0.000001363368,0.0005350281],"genre_scores_gemma":[0.998749,0.0002778993,0.0006453106,0.0001218535,0.00001838937,0.000001776342,0.00002657935,0.000004073308,0.0001551597],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7910107,"threshold_uncertainty_score":0.1898882,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005294375468203335,"score_gpt":0.2212092360234154,"score_spread":0.215914860555212,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}