{"id":"W1984840383","doi":"10.1074/jbc.m005067200","title":"Intercellular Adhesion Molecule-1 (ICAM-1) Gene Expression in Human T Cells Is Regulated by Phosphotyrosyl Phosphatase Activity","year":2001,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre hospitalier universitaire de Québec; Université Laval","funders":"","keywords":"ICAM-1; Cell biology; Intercellular Adhesion Molecule-1; Protein tyrosine phosphatase; Phosphatase; Biology; Reporter gene; Intercellular adhesion molecule; Cell adhesion molecule; Intracellular; Transfection; Cell adhesion; Molecular biology; Adhesion; Gene expression; Signal transduction; Chemistry; Gene; Phosphorylation; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005207657,0.0001549055,0.0001310249,0.000174116,0.00009093003,0.0002547551,0.00005406535,0.0001657468,0.0009257027],"category_scores_gemma":[0.00008046917,0.00006810474,0.0001442801,0.00024485,0.00009230171,0.00009472728,0.0001338279,0.0003082916,0.000224623],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001110499,"about_ca_system_score_gemma":0.00007308285,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003250811,"about_ca_topic_score_gemma":0.0002624131,"domain_scores_codex":[0.9999079,0.00001194067,0.000005790188,0.00002202429,0.00002121108,0.00003116628],"domain_scores_gemma":[0.9999641,0.000006720297,0.00001254971,0.000002637425,0.00000596971,0.00000809321],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006750022,0.00001662554,0.000570858,0.0000286621,0.000003646021,0.00006456937,0.00002659522,0.00002493881,0.9970323,0.00004828211,0.0000397406,0.002076219],"study_design_scores_gemma":[0.00003215777,0.0006231482,0.0585038,0.00001493822,0.00004247676,0.0009470344,0.0001214905,0.001213425,0.9331679,0.000183644,0.005141812,0.000008176978],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924954,0.003892189,0.001900615,0.00006656387,0.00001986433,0.00001961569,0.0002756994,0.00004628473,0.001283721],"genre_scores_gemma":[0.9958254,0.001966997,0.0008066688,0.00003981024,0.00001752851,0.00002928774,0.0003190046,0.000004547068,0.0009908135],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009257027,"threshold_uncertainty_score":0.003096759,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02865234222701422,"score_gpt":0.2975678509661971,"score_spread":0.2689155087391829,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}