{"id":"W1984857099","doi":"10.1139/o05-059","title":"NTP-driven translocation and regulation of downstream template opening by multi-subunit RNA polymerases","year":2005,"lang":"en","type":"review","venue":"Biochemistry and Cell Biology","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Institutes of Health; Michigan State University","keywords":"Biophysics; Polymerase; RNA polymerase; RNA; Protein subunit; Biology; Cell biology; Binding site; Transcription (linguistics); Biochemistry; Chemistry; DNA; Gene","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003703624,0.0008090772,0.001301906,0.001132697,0.0002141369,0.0007391202,0.001148018,0.001238678,0.001146906],"category_scores_gemma":[0.0002977915,0.0003698245,0.0002631726,0.001160764,0.0005378356,0.001193707,0.0004734029,0.00100518,0.002291723],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008147869,"about_ca_system_score_gemma":0.0004850999,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000606645,"about_ca_topic_score_gemma":0.0008693049,"domain_scores_codex":[0.9998837,0.00001657514,0.00001444439,0.00002554201,0.00004383495,0.00001590432],"domain_scores_gemma":[0.9998848,0.00003895833,0.00002277346,0.00000535563,0.00003148068,0.00001661745],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001791154,0.00008715172,0.0002738213,0.01042275,0.00006785389,0.0006262247,0.00008630897,0.001223941,0.01439812,0.008467453,0.01777769,0.9463896],"study_design_scores_gemma":[0.00004791986,0.0001409531,0.001533686,0.001325886,0.00006027563,0.002333611,0.00006954587,0.0003604531,0.004618503,0.005215546,0.984266,0.00002765241],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005046183,0.9974304,0.0003379235,0.0001653212,0.0001767868,0.000004171505,0.000008358806,0.00001275697,0.001359594],"genre_scores_gemma":[0.002345288,0.9959644,0.0002458851,0.0001293553,0.0001897706,0.000007965917,0.00002388928,0.000001644459,0.001091854],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001301906,"threshold_uncertainty_score":0.005911648,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02300423678939871,"score_gpt":0.281577359984207,"score_spread":0.2585731231948083,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}