{"id":"W1984860579","doi":"10.1152/ajpendo.00254.2009","title":"TIP39/parathyroid hormone type 2 receptor signaling is a potent inhibitor of chondrocyte proliferation and differentiation","year":2009,"lang":"en","type":"article","venue":"American Journal of Physiology-Endocrinology and Metabolism","topic":"NF-κB Signaling Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research","keywords":"Chondrocyte; Cell biology; Receptor; Signal transduction; Internal medicine; Cyclin-dependent kinase; MAPK/ERK pathway; Transfection; Biology; Parathyroid hormone; Transcription factor; Endocrinology; Chemistry; Cell culture; Cell cycle; Cartilage; Cell; Medicine; Calcium; Anatomy; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000124756,0.0001834049,0.0004827207,0.0001233226,0.00007654875,0.000008969218,0.0001120383,0.0000907986,0.00000557094],"category_scores_gemma":[0.00007176099,0.0001542741,0.00008661659,0.0001114425,0.0002936734,0.0000167502,0.00004541859,0.0002124582,0.000001315884],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006397541,"about_ca_system_score_gemma":0.00006304753,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004903916,"about_ca_topic_score_gemma":4.832052e-7,"domain_scores_codex":[0.9987875,0.0001777559,0.0004294503,0.0002583195,0.0001021078,0.0002448758],"domain_scores_gemma":[0.9988888,0.00002152477,0.0005948027,0.0001522401,0.0002503012,0.00009236688],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007042731,0.00008134026,0.0001692301,0.000005496256,0.0001198057,0.000001431933,0.0002192221,0.00001657238,0.9892268,0.0001674665,0.0003055273,0.008982874],"study_design_scores_gemma":[0.001235078,0.002786329,0.07203427,0.00001447104,0.0001150494,0.0001510193,0.0001587746,0.00001693276,0.9209577,0.0004582401,0.001897871,0.0001742734],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910142,0.008081744,0.000292316,0.0003109086,0.0001707818,0.00009959847,0.00001034839,0.000005725852,0.00001438202],"genre_scores_gemma":[0.9941677,0.003352025,0.00151873,0.0004643495,0.0004391243,0.000002443501,0.00001712504,0.00001135349,0.00002716398],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07186504,"threshold_uncertainty_score":0.6291116,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00699974815026062,"score_gpt":0.2301349301678023,"score_spread":0.2231351820175417,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}