{"id":"W1984864188","doi":"10.1002/jnr.20425","title":"An 8.5-kb segment of the PMP22 promoter responds to loss of axon signals during Wallerian degeneration, but does not respond to specific axonal signals during nerve regeneration","year":2005,"lang":"en","type":"article","venue":"Journal of Neuroscience Research","topic":"Hereditary Neurological Disorders","field":"Neuroscience","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Royal Victoria Hospital; Montreal Neurological Institute and Hospital; McGill University","funders":"McGill University","keywords":"Wallerian degeneration; Biology; Transgene; Remyelination; Axon; Myelin; Schwann cell; Cell biology; Neuroscience; Gene; Molecular biology; Genetics; Central nervous system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004183713,0.0002724341,0.0004261626,0.001062149,0.0006945842,0.0002546589,0.002141799,0.0001106385,0.0001329681],"category_scores_gemma":[0.004234795,0.0001753184,0.0001945082,0.002277604,0.0005711368,0.001114132,0.0004848663,0.0007960323,0.00001272678],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001932221,"about_ca_system_score_gemma":0.0003862543,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008794972,"about_ca_topic_score_gemma":0.00002349929,"domain_scores_codex":[0.990281,0.002649783,0.00139591,0.0008598334,0.003905685,0.0009078126],"domain_scores_gemma":[0.9967808,0.000501194,0.0005142678,0.0007900234,0.0008198901,0.0005938009],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001572302,0.0003857673,0.0004798399,0.00002881751,0.000001896116,0.0001367865,0.0006022984,0.03168992,0.9644006,0.00005745102,0.00009829043,0.0005459621],"study_design_scores_gemma":[0.0004968753,0.001954014,0.04583434,0.00007345348,0.000003622003,0.0001460637,0.00009243251,0.0007605564,0.9498872,0.0000746755,0.000505318,0.0001714628],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9850426,0.00002035142,0.0001848715,0.01335461,0.0004176779,0.0008658996,0.00005226444,0.00001462887,0.0000470559],"genre_scores_gemma":[0.9975682,0.00007181984,0.0004288633,0.0006616821,0.0004787376,0.00002361922,2.905241e-7,0.00003230847,0.0007344704],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0453545,"threshold_uncertainty_score":0.7149276,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1111217064767439,"score_gpt":0.3634085085153163,"score_spread":0.2522868020385724,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}