{"id":"W1984878005","doi":"10.1002/stem.298","title":"Distinguishing Between Mouse and Human Pluripotent Stem Cell Regulation: The Best Laid Plans of Mice and Men","year":2010,"lang":"en","type":"review","venue":"Stem Cells","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":91,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Population Health Research Institute","funders":"","keywords":"Biology; Epigenome; Induced pluripotent stem cell; Transcriptome; Stem cell; Transcription factor; Cell biology; Computational biology; Transcriptional regulation; Embryonic stem cell; Genetics; Cellular differentiation; Gene regulatory network; Gene; Gene expression; DNA methylation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006820821,0.0004438111,0.0009107503,0.00008276032,0.0002475409,0.0001037238,0.0005635306,0.0005619542,0.000005770937],"category_scores_gemma":[0.000006653968,0.0003205374,0.0001964921,0.0001045364,0.0002680568,0.000006053843,0.0006214921,0.0005163528,0.00001074397],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002395224,"about_ca_system_score_gemma":0.0001039289,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005761164,"about_ca_topic_score_gemma":0.00003272666,"domain_scores_codex":[0.9975755,0.0003146733,0.0006701587,0.0007023895,0.0003449645,0.0003922916],"domain_scores_gemma":[0.998301,0.0001468671,0.0005207037,0.0007571931,0.000105349,0.0001688315],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000435735,0.0002289034,0.0009579201,0.05838517,0.0008707232,0.0000335895,0.0004924804,0.000008802825,0.3152196,0.0001195022,0.002373671,0.6212661],"study_design_scores_gemma":[0.0003079595,0.0001665581,0.0000278881,0.001240014,0.0004206011,0.00001710068,0.0001329734,0.000003746209,0.03729919,0.00000530858,0.9599533,0.0004253621],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02624322,0.9683751,0.00002803499,0.00002771094,0.0001285832,0.001307529,0.0006199862,0.00001359973,0.003256193],"genre_scores_gemma":[0.01551087,0.9696071,0.00008121238,0.000007271864,0.0004751535,0.00004761873,0.00036252,0.0001050022,0.01380323],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9575796,"threshold_uncertainty_score":0.9999247,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03363691629099125,"score_gpt":0.2946333872448917,"score_spread":0.2609964709539005,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}