{"id":"W1984939227","doi":"10.1371/journal.pone.0004582","title":"Association and Mutation Analyses of 16p11.2 Autism Candidate Genes","year":2009,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Autism Spectrum Disorder Research","field":"Neuroscience","cited_by":95,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Hospital for Sick Children; SickKids Foundation","funders":"National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; Autism Speaks","keywords":"Autism; Genetics; Candidate gene; Biology; Copy-number variation; Heritability of autism; Neurodevelopmental disorder; Gene; Gene duplication; Medicine; Genome; Phenotype; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001243271,0.00006214326,0.0001410196,0.0001168317,0.00007284986,0.00002989521,0.000085767,0.0000410954,0.0000588673],"category_scores_gemma":[0.0003720245,0.00006180033,0.00001821848,0.0002819897,0.00002741118,0.0001456638,0.00002246254,0.00008138517,0.00002022756],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005171205,"about_ca_system_score_gemma":0.00002533153,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001203594,"about_ca_topic_score_gemma":0.00002696838,"domain_scores_codex":[0.9989129,0.00009217288,0.0001442104,0.0001905684,0.0004818687,0.000178301],"domain_scores_gemma":[0.9995974,0.0001154057,0.0001148216,0.0001176023,0.0000126495,0.00004212082],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001127354,0.0003142104,0.005197737,0.00001676177,0.00002249669,0.000004898447,0.0001575605,0.00000770968,0.9906405,0.00219361,0.00001760961,0.001415673],"study_design_scores_gemma":[0.0002486888,0.0001240728,0.1206911,0.00001828265,0.00004709207,9.25817e-7,0.000006786411,0.002907527,0.8686029,0.007277569,0.000007644836,0.00006740592],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919161,0.0002072215,0.00005176585,0.006617751,0.000007393105,0.0001465883,0.00001268928,0.0000401457,0.001000306],"genre_scores_gemma":[0.9984258,0.0003878037,0.0002402479,0.0001077175,0.00001000619,0.000004424884,0.000003178211,0.000005911003,0.000814954],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1220376,"threshold_uncertainty_score":0.2520145,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08625854167508742,"score_gpt":0.3310578402538767,"score_spread":0.2447992985787893,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}