{"id":"W1985024291","doi":"10.3727/000000007783465244","title":"Combination of Anti-CD4 with Anti-LFA-1 and Anti-CD154 Monoclonal Antibodies Promotes Long-Term Survival and Function of Neonatal Porcine Islet Xenografts in Spontaneously Diabetic NOD Mice","year":2007,"lang":"en","type":"article","venue":"Cell Transplantation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"NOD mice; Xenotransplantation; Islet; Medicine; Nod; Monoclonal antibody; Transplantation; Type 1 diabetes; CD154; Immunology; Cancer research; Antibody; Endocrinology; Internal medicine; Diabetes mellitus; CD40; Biology; Cytotoxic T cell; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003267169,0.0005706977,0.000543737,0.0003493253,0.0001497387,0.0003078402,0.0003774108,0.0003870119,0.0007198841],"category_scores_gemma":[0.0001429588,0.0001840023,0.0004596427,0.0001392891,0.0001934329,0.0003566946,0.0001918757,0.001157493,0.0003152175],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001721379,"about_ca_system_score_gemma":0.0001890992,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003016769,"about_ca_topic_score_gemma":0.0005469705,"domain_scores_codex":[0.9997147,0.00005451025,0.00003795755,0.00005771806,0.00005353521,0.00008157797],"domain_scores_gemma":[0.9996972,0.00003933601,0.0000734015,0.00002617952,0.0000193909,0.0001445187],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008616518,0.0006540012,0.0002356793,0.00006034032,0.00001716969,0.00006286506,0.00003117384,0.0001157198,0.9954599,0.00004928705,0.0000762504,0.002375963],"study_design_scores_gemma":[0.0001581839,0.01147203,0.006436469,0.00002805364,0.0000833736,0.0004077841,0.00005992115,0.001686692,0.9772466,0.00004455438,0.002364263,0.00001202666],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958553,0.001517142,0.001091022,0.0001046527,0.00007288528,0.00003432821,0.0001693556,0.00007622717,0.001079071],"genre_scores_gemma":[0.9939659,0.001108968,0.001602491,0.0001206734,0.00004372988,0.00007809155,0.0003972412,0.00003312544,0.002649831],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007198841,"threshold_uncertainty_score":0.002408206,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009400373810273251,"score_gpt":0.2252042248805548,"score_spread":0.2158038510702816,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}