{"id":"W1985141290","doi":"10.1038/nrgastro.2011.172","title":"Optimization of conventional therapy in patients with IBD","year":2011,"lang":"en","type":"review","venue":"Nature Reviews Gastroenterology & Hepatology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":90,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Thomas Hospital","funders":"","keywords":"Medicine; Intensive care medicine; Dosing; Context (archaeology); Regimen; Drug; Pharmacotherapy; Combination therapy; Pharmacology; Surgery; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0003641287,0.0005841723,0.002033093,0.0002676728,0.00002792388,0.000003967992,0.0005065256,0.001397145,0.0001461513],"category_scores_gemma":[0.00008058553,0.0004364042,0.000543949,0.0001300573,0.000268382,0.000006946361,0.0001278831,0.0007179957,0.0000153234],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004232635,"about_ca_system_score_gemma":0.0002096976,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002321888,"about_ca_topic_score_gemma":0.00005414801,"domain_scores_codex":[0.9963592,0.001187155,0.001138241,0.0007385171,0.0001211486,0.0004557436],"domain_scores_gemma":[0.9978386,0.00001539954,0.001151629,0.0007030225,0.0001960132,0.00009529758],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.004250088,0.001555979,0.7384641,0.01121927,0.001185214,0.00009168049,0.00001619964,0.00002410427,0.000001578666,0.0002730806,0.002475988,0.2404428],"study_design_scores_gemma":[0.002391254,0.001248846,0.01156243,0.001705441,0.0003416621,0.00005001939,5.28141e-7,0.00000251807,0.000001043034,0.00000518449,0.9823902,0.0003008546],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005224533,0.9922605,0.0002060846,0.000006685704,0.0002936419,0.001828233,0.00009540491,0.000008377906,0.00007652494],"genre_scores_gemma":[0.0006435564,0.995414,0.0009237103,0.0003309876,0.00007716302,0.0003042365,0.002216693,0.00006866393,0.00002094779],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9799142,"threshold_uncertainty_score":0.9998993,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01278697157756091,"score_gpt":0.269119478156439,"score_spread":0.2563325065788781,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}