{"id":"W1985173430","doi":"10.1016/j.freeradbiomed.2010.12.038","title":"Resveratrol interacts with estrogen receptor-β to inhibit cell replicative growth and enhance stress resistance by upregulating mitochondrial superoxide dismutase","year":2011,"lang":"en","type":"article","venue":"Free Radical Biology and Medicine","topic":"Sirtuins and Resveratrol in Medicine","field":"Medicine","cited_by":66,"is_retracted":false,"has_abstract":false,"ca_institutions":"Brock University","funders":"","keywords":"Downregulation and upregulation; Estrogen receptor; Biology; Superoxide dismutase; Cell biology; Oxidative stress; Resveratrol; Cell growth; Cancer research; Endocrinology; Pharmacology; Biochemistry; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000270041,0.0003589551,0.0007679104,0.0001287353,0.0001775939,0.000007044365,0.0001826959,0.0002730942,0.0001707561],"category_scores_gemma":[0.001029136,0.0002184015,0.00003876338,0.0002393154,0.001458347,0.0000753279,0.0001164956,0.0005532227,0.000004526523],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003432843,"about_ca_system_score_gemma":0.00006334743,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001894013,"about_ca_topic_score_gemma":0.00003680522,"domain_scores_codex":[0.9977563,0.0001502103,0.0005163684,0.0008413967,0.0002468051,0.0004888982],"domain_scores_gemma":[0.9980636,0.0003147467,0.000151996,0.0005466014,0.0001154593,0.0008075477],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.009638038,0.0003994409,0.03276888,0.0003394546,0.0002857095,0.0002413885,0.004075838,1.040315e-7,0.8939334,0.002472025,0.05153112,0.004314648],"study_design_scores_gemma":[0.02555364,0.02136794,0.01055001,0.0042236,0.0008708012,0.0005198469,0.002436365,0.00002958445,0.9056162,0.001524996,0.02622315,0.001083927],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9764059,0.006889248,0.001505423,0.01133074,0.0002679458,0.0008179212,0.0001007216,0.00007068775,0.002611444],"genre_scores_gemma":[0.9870852,0.0006604242,0.007962147,0.00228615,0.000876286,0.00008023967,0.0001762688,0.00003575368,0.0008374776],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02530797,"threshold_uncertainty_score":0.8906155,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008785752927791612,"score_gpt":0.2579763762575389,"score_spread":0.2491906233297473,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}