{"id":"W1985240742","doi":"10.1007/s001340051122","title":"Clinical trials of mediator-directed therapy in sepsis: what have we learned?","year":2000,"lang":"en","type":"review","venue":"Intensive Care Medicine","topic":"Sepsis Diagnosis and Treatment","field":"Medicine","cited_by":112,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Toronto General Hospital; University Health Network","funders":"","keywords":"Medicine; Intensive care medicine; Clinical trial; Sepsis; Randomized controlled trial; Septic shock; Bioinformatics; Immunology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008539962,0.001580509,0.009017991,0.001702166,0.0004494528,0.003152735,0.002429322,0.003433869,0.003857477],"category_scores_gemma":[0.0125893,0.0006084771,0.002226438,0.003160664,0.001212176,0.003141165,0.0009445511,0.003850283,0.001139246],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001165334,"about_ca_system_score_gemma":0.003488614,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001638927,"about_ca_topic_score_gemma":0.003598826,"domain_scores_codex":[0.998287,0.0007199561,0.0003849302,0.0001850517,0.0003411831,0.00008173338],"domain_scores_gemma":[0.9887282,0.008814811,0.001001167,0.000170904,0.0009852534,0.0002997211],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001648819,0.0001895206,0.0003474953,0.1027729,0.001480091,0.0001616702,0.00009699798,0.0003613948,0.0008114009,0.002585541,0.02476835,0.8647758],"study_design_scores_gemma":[0.003757378,0.002573357,0.004020919,0.1455537,0.00960379,0.001272182,0.0004942401,0.0003905041,0.0008974852,0.008043265,0.8232604,0.0001328395],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000588278,0.9990109,0.00005200832,0.0005655487,0.0001719841,0.000007684444,0.00001077657,0.000002675733,0.0001195443],"genre_scores_gemma":[0.0007831238,0.9975821,0.000278809,0.0009869554,0.0002551035,0.00002190776,0.00001772283,0.00000186995,0.00007242199],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.009017991,"threshold_uncertainty_score":0.04516417,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.4767524202816152,"score_gpt":0.5454266647203345,"score_spread":0.06867424443871928,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}