{"id":"W1985281315","doi":"10.1139/y03-032","title":"Synthesis and degradation of endothelin-1","year":2003,"lang":"en","type":"review","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":105,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Gene isoform; Endothelins; Endothelin receptor; Chymase; Enzyme; Biochemistry; Alternative splicing; Chemistry; Endothelin 1; Phosphoramidon; Peptide; Proteolysis; Biology; Neprilysin; Cell biology; Gene; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004113315,0.0005938776,0.0007161392,0.0005460152,0.0002169671,0.0009323139,0.0004115547,0.0007048696,0.001743229],"category_scores_gemma":[0.0004217863,0.0002138156,0.0004566699,0.0004497482,0.000257719,0.0008018616,0.0004710837,0.0009857754,0.001625551],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005070666,"about_ca_system_score_gemma":0.0006105673,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003541526,"about_ca_topic_score_gemma":0.0003382987,"domain_scores_codex":[0.999619,0.00004606848,0.00007137695,0.0001008124,0.0001114805,0.0000511834],"domain_scores_gemma":[0.9998618,0.00001886224,0.00003461709,0.000009349659,0.00005510376,0.00002033168],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004854107,0.000146398,0.001267928,0.01884741,0.0002888184,0.002348485,0.0003734562,0.001149592,0.4882315,0.01857768,0.01661333,0.4516701],"study_design_scores_gemma":[0.00006699055,0.0006675175,0.007647308,0.001487275,0.0002143244,0.006860201,0.0001905568,0.0006993575,0.2115285,0.005757177,0.7647966,0.00008419743],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01086524,0.9722928,0.005931889,0.0008466963,0.001210634,0.00005014996,0.0004514984,0.00006098371,0.008290099],"genre_scores_gemma":[0.07327552,0.9039501,0.005464735,0.001029197,0.001245651,0.0001122218,0.001193793,0.00002873167,0.01369999],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001743229,"threshold_uncertainty_score":0.005831659,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03559706376898131,"score_gpt":0.3249968073624359,"score_spread":0.2893997435934546,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}