{"id":"W1985287781","doi":"10.1038/ncb854","title":"Elimination of host cell PtdIns(4,5)P2 by bacterial SigD promotes membrane fission during invasion by Salmonella","year":2002,"lang":"en","type":"article","venue":"Nature Cell Biology","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":272,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; University of British Columbia; Hospital for Sick Children","funders":"","keywords":"Membrane ruffling; Cell biology; Internalization; Vacuole; Biology; Endocytosis; Phosphatidylinositol; Salmonella; Cell; Signal transduction; Biochemistry; Cytoskeleton; Cytoplasm; Bacteria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002064506,0.0003036955,0.0003117684,0.0002156593,0.0002738383,0.0006467039,0.0001974898,0.0003644262,0.0006606769],"category_scores_gemma":[0.0001875485,0.000300688,0.0003559184,0.0001519577,0.0003634763,0.0003261337,0.0005168589,0.0009254171,0.0004749412],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008520907,"about_ca_system_score_gemma":0.0003358369,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008347323,"about_ca_topic_score_gemma":0.001550301,"domain_scores_codex":[0.9998069,0.00002525264,0.00001653525,0.00002034328,0.00005119435,0.00007961665],"domain_scores_gemma":[0.9998119,0.0000469815,0.00003448495,0.00003083909,0.00002089578,0.00005496744],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003180784,0.00001573957,0.0001871726,0.00001431999,0.000002143814,0.00006234205,0.00001506185,0.0000528424,0.9987547,0.0001563724,0.00003580645,0.0003853361],"study_design_scores_gemma":[0.00001621855,0.00009021808,0.003188371,0.000002708077,0.000004453718,0.0001425064,0.00004801628,0.0009555054,0.9949368,0.00004308953,0.0005683131,0.000003652529],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974112,0.0004074588,0.001225434,0.0001020098,0.00001850193,0.000005769168,0.00009135482,0.00004216647,0.0006960478],"genre_scores_gemma":[0.997803,0.0001278997,0.0006748192,0.00003004583,0.000005166203,0.000008524586,0.0002062072,0.00002034725,0.001123882],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008520907,"threshold_uncertainty_score":0.006182373,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005011581466362968,"score_gpt":0.2062656219464448,"score_spread":0.2012540404800818,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}