{"id":"W1985291169","doi":"10.1007/s00395-014-0424-y","title":"Targeting MMP-2 to treat ischemic heart injury","year":2014,"lang":"en","type":"review","venue":"Basic Research in Cardiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":95,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Matrix metalloproteinase; Medicine; Myocardial infarction; Ischemia; Cardiology; Heart failure; Intracellular; Clinical trial; Reperfusion injury; Ischemic injury; Extracellular matrix; Bioinformatics; Internal medicine; Neuroscience; Biology; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004277266,0.0009424462,0.00125665,0.001403986,0.0001835179,0.0007603684,0.0007238949,0.0008063337,0.002470806],"category_scores_gemma":[0.0004856574,0.0002699891,0.0004191885,0.001118533,0.0004358796,0.0007746698,0.0004617115,0.00232739,0.001687583],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003778383,"about_ca_system_score_gemma":0.0006168004,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000666392,"about_ca_topic_score_gemma":0.001708603,"domain_scores_codex":[0.9998816,0.00001327941,0.00001430792,0.00002085066,0.00005417004,0.00001579895],"domain_scores_gemma":[0.9998612,0.00005148233,0.0000250331,0.000005545439,0.00003824536,0.00001841675],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001519369,0.0001722868,0.000124834,0.00744537,0.0001039788,0.0002239122,0.00002984924,0.0004524894,0.006666401,0.002576449,0.0357641,0.9462884],"study_design_scores_gemma":[0.0001304681,0.0002292982,0.0009671032,0.001786239,0.000241248,0.001508744,0.00004174456,0.000322202,0.003356629,0.002587963,0.9887939,0.0000344158],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000349612,0.9969419,0.0004828542,0.0003906469,0.0003389922,0.0000107783,0.0000363536,0.00001969324,0.00142906],"genre_scores_gemma":[0.001870321,0.9956902,0.0004870311,0.0003218629,0.0002657676,0.00001415816,0.00005807343,0.000003542117,0.001289104],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002470806,"threshold_uncertainty_score":0.008265615,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.109381496487629,"score_gpt":0.4514154317373173,"score_spread":0.3420339352496883,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}