{"id":"W1985380203","doi":"10.1136/ard.2007.080960","title":"Synovial tissue response to rituximab: mechanism of action and identification of biomarkers of response","year":2007,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":329,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Dutch Arthritis Association","keywords":"Medicine; Rituximab; Rheumatoid arthritis; Rheumatology; Internal medicine; Autoantibody; Rheumatoid factor; Gastroenterology; Antibody; Immunology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001562387,0.0005152212,0.001367716,0.0008794294,0.0002296945,0.001221922,0.0004324319,0.001019303,0.001616815],"category_scores_gemma":[0.002300454,0.000247194,0.000595067,0.000441513,0.0003937319,0.000621988,0.0002324491,0.0009426048,0.0005026028],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005508022,"about_ca_system_score_gemma":0.0003384587,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000359082,"about_ca_topic_score_gemma":0.0001942119,"domain_scores_codex":[0.9987465,0.0006405007,0.00008232718,0.0001032803,0.000248412,0.0001790745],"domain_scores_gemma":[0.9989514,0.0003613467,0.0003247916,0.00008041073,0.0001935792,0.00008844024],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.01693771,0.001292773,0.09425266,0.001175472,0.0005483457,0.00318166,0.0003963912,0.001506003,0.7377036,0.001503312,0.00154163,0.1399603],"study_design_scores_gemma":[0.002460617,0.03232589,0.4935949,0.0004050819,0.001734074,0.02096386,0.0009424276,0.0121846,0.4157546,0.003121044,0.01637833,0.0001346089],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9362995,0.04796898,0.006626314,0.001401046,0.000223758,0.0003595535,0.0003128134,0.0001480368,0.006659919],"genre_scores_gemma":[0.9959152,0.001901143,0.001024177,0.0002343587,0.0001389307,0.00006328381,0.0001105047,0.000007137818,0.0006052902],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001616815,"threshold_uncertainty_score":0.008262813,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03733941556840234,"score_gpt":0.3622175522666128,"score_spread":0.3248781366982105,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}