{"id":"W1985380203","doi":"10.1136/ard.2007.080960","title":"Synovial tissue response to rituximab: mechanism of action and identification of biomarkers of response","year":2007,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":329,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Dutch Arthritis Association","keywords":"Medicine; Rituximab; Rheumatoid arthritis; Rheumatology; Internal medicine; Autoantibody; Rheumatoid factor; Gastroenterology; Antibody; Immunology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00218893,0.00009782307,0.0003831642,0.0003123652,0.00004274639,0.000006328306,0.0001474895,0.0000415797,0.00004390057],"category_scores_gemma":[0.003888989,0.00007371171,0.0001158065,0.0003131668,0.0003007142,0.00009152637,0.00006444599,0.00004043979,0.000002748373],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000099902,"about_ca_system_score_gemma":0.0001292625,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001074384,"about_ca_topic_score_gemma":0.000008754917,"domain_scores_codex":[0.9981843,0.0003252915,0.0006788712,0.0001319785,0.0005144696,0.0001651201],"domain_scores_gemma":[0.9978999,0.0008004535,0.0003961814,0.0004234685,0.0003361245,0.000143838],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.05463461,0.0008794437,0.001096515,0.0009203686,0.0003685482,0.000003214774,0.001214657,0.000003157864,0.8544767,0.001046188,0.0006493722,0.08470725],"study_design_scores_gemma":[0.001343605,0.0007951504,0.2318102,0.001382778,0.00002645167,0.00001008317,0.0009154917,0.00004191633,0.7615443,0.001944661,0.0001201325,0.0000652412],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954053,0.001883406,0.0005048213,0.001489911,0.00007872193,0.0004974047,0.0001096559,0.000009547294,0.00002124378],"genre_scores_gemma":[0.998207,0.001477079,0.0001688805,0.00002713977,0.000006021118,0.000008253151,0.00000358607,0.00001202578,0.00009007067],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2307137,"threshold_uncertainty_score":0.4655764,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03733941556840234,"score_gpt":0.3622175522666128,"score_spread":0.3248781366982105,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}